Literature DB >> 2925527

DC 107, a novel antitumor antibiotic produced by a Streptomyces sp.

M Hara1, I Takahashi, M Yoshida, K Asano, I Kawamoto, M Morimoto, H Nakano.   

Abstract

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Year:  1989        PMID： 2925527     DOI： 10.7164/antibiotics.42.333

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


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  20 in total

1.  DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences.

Authors:  Velliyur Viswesh; Allison M Hays; Kent Gates; Daekyu Sun
Journal:  Bioorg Med Chem       Date:  2012-05-23       Impact factor: 3.641

2.  Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.

Authors:  Mostafa I Fekry; Jozsef Szekely; Sanjay Dutta; Leonid Breydo; Hong Zang; Kent S Gates
Journal:  J Am Chem Soc       Date:  2011-10-18       Impact factor: 15.419

3.  N-thiolated beta-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus.

Authors:  Kevin D Revell; Bart Heldreth; Timothy E Long; Seyoung Jang; Edward Turos
Journal:  Bioorg Med Chem       Date:  2006-12-20       Impact factor: 3.641

Review 4.  Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

Authors:  Abraham J Waldman; Tai L Ng; Peng Wang; Emily P Balskus
Journal:  Chem Rev       Date:  2017-04-04       Impact factor: 60.622

5.  Synthesis and characterization of a small analogue of the anticancer natural product leinamycin.

Authors:  Kripa Keerthi; Anuruddha Rajapakse; Daekyu Sun; Kent S Gates
Journal:  Bioorg Med Chem       Date:  2012-10-27       Impact factor: 3.641

Review 6.  Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts.

Authors:  Christiana N Teijaro; Ajeeth Adhikari; Ben Shen
Journal:  J Ind Microbiol Biotechnol       Date:  2018-11-13       Impact factor: 3.346

7.  Entering the leinamycin rearrangement via 2-(trimethylsilyl)ethyl sulfoxides.

Authors:  Kripa Keerthi; Kent S Gates
Journal:  Org Biomol Chem       Date:  2007-04-13       Impact factor: 3.876

8.  P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities.

Authors:  Thomas Kwong; Ming Ma; Guohui Pan; Dong Yang; Chunying Yang; Jeremy R Lohman; Jeffrey D Rudolf; John L Cleveland; Ben Shen
Journal:  Biochemistry       Date:  2018-08-02       Impact factor: 3.162

9.  Characterization of DNA damage induced by a natural product antitumor antibiotic leinamycin in human cancer cells.

Authors:  Velliyur Viswesh; Kent Gates; Daekyu Sun
Journal:  Chem Res Toxicol       Date:  2010-01       Impact factor: 3.739

10.  Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140.

Authors:  Yi-Qiang Cheng; Gong-Li Tang; Ben Shen
Journal:  J Bacteriol       Date:  2002-12       Impact factor: 3.490
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