Literature DB >> 29254060

Synthesis of carbohydrate conjugated 6A,6D-bifunctionalized β cyclodextrin derivatives as potential liver cancer drug carriers.

Yili Ding1, Chamakura V N S Vara Prasad2, Charles Ding3, Bingyun Wang4.   

Abstract

Galactosyl and lactosyl conjugated 6A,6D-bifunctionlized β cyclodextrin derivatives were designed and synthesized as the potential liver cancer drug carriers through SN2 replacement and click reactions in order to increase liver cancer drug's targeting ability, solubility and stability. The synthetic methods and strategies to obtain the designed compounds were discussed.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Keywords:  Bifunctionalized cyclodextrin; Cancer drug carrier,Click reaction; Synthesis

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Year:  2017        PMID: 29254060     DOI: 10.1016/j.carbpol.2017.11.054

Source DB:  PubMed          Journal:  Carbohydr Polym        ISSN: 0144-8617            Impact factor:   9.381


  1 in total

1.  Formation of inclusion complex of enrofloxacin with 2-hydroxypropyl-β-cyclodextrin.

Authors:  Yili Ding; Yuchang Pang; Chamakura V N S Vara Prasad; Bingyun Wang
Journal:  Drug Deliv       Date:  2020-12       Impact factor: 6.419

  1 in total

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