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Literature DB >> 2925255

Effect of immunoglobulin M from normal human serum on Leishmania donovani promastigote agglutination, complement-mediated killing, and phagocytosis by human monocytes.

Abstract

Serum from healthy, nonimmune humans contained immunoglobulin M (IgM) antibodies that agglutinated Leishmania donovani promastigotes, activated complement, and enhanced promastigote ingestion by human monocytes. The findings indicate that IgM antibodies have the capacity to affect the initial interaction of L. donovani promastigotes with human host defenses.

Entities: Disease Species

Mesh：

Substances：
Immunoglobulin M

Year: 1989 PMID： 2925255 PMCID： PMC313275 DOI： 10.1128/iai.57.4.1343-1346.1989

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

8 in total

1. Roles of CR3 and mannose receptors in the attachment and ingestion of Leishmania donovani by human mononuclear phagocytes.

Authors: M E Wilson; R D Pearson
Journal: Infect Immun Date: 1988-02 Impact factor: 3.441

2. A simple monophasic medium for axenic culture of hemoflagellates.

Authors: R L Berens; R Brun; S M Krassner
Journal: J Parasitol Date: 1976-06 Impact factor: 1.276

3. Leishmania species: mechanisms of complement activation by five strains of promastigotes.

Authors: D M Mosser; S K Burke; E E Coutavas; J F Wedgwood; P J Edelson
Journal: Exp Parasitol Date: 1986-12 Impact factor: 2.011

4. Differential survival of Leishmania donovani amastigotes in human monocytes.

Authors: R D Pearson; J L Harcus; D Roberts; G R Donowitz
Journal: J Immunol Date: 1983-10 Impact factor: 5.422

5. Antileishmanial activity of chlorpromazine.

Authors: R D Pearson; A A Manian; D Hall; J L Harcus; E L Hewlett
Journal: Antimicrob Agents Chemother Date: 1984-05 Impact factor: 5.191

6. Mechanism of lethal effect of human serum upon Leishmania donovani.

Authors: R D Pearson; R T Steigbigel
Journal: J Immunol Date: 1980-11 Impact factor: 5.422

7. Evidence that Leishmania donovani utilizes a mannose receptor on human mononuclear phagocytes to establish intracellular parasitism.

Authors: M E Wilson; R D Pearson
Journal: J Immunol Date: 1986-06-15 Impact factor: 5.422

8. Macrophage complement and lectin-like receptors bind Leishmania in the absence of serum.

Authors: J M Blackwell; R A Ezekowitz; M B Roberts; J Y Channon; R B Sim; S Gordon
Journal: J Exp Med Date: 1985-07-01 Impact factor: 14.307

8 in total

9 in total

Review 1. Human poly- and cross-reactive anti-viral antibodies and their impact on protection and pathology.

Authors: Lucile Warter; Ramapraba Appanna; Katja Fink
Journal: Immunol Res Date: 2012-09 Impact factor: 2.829

2. Purification and characterization of alpha-toxin produced by Clostridium novyi type A.

Authors: D W Ball; R L Van Tassell; M D Roberts; P E Hahn; D M Lyerly; T D Wilkins
Journal: Infect Immun Date: 1993-07 Impact factor: 3.441

3. Cationic glycoproteins in sera of patients with acute infections identified as kappa light chain glycosylated IgG.

Authors: K Ritter; A Wiebusch; M Mäder; H Eiffert; H Kratzin; R Thomssen
Journal: Med Microbiol Immunol Date: 1993-07 Impact factor: 3.402

4. Specific and natural antibody production during Salmonella typhimurium infection in genetically susceptible and resistant mice.

Authors: P Matsiota-Bernard; W Mahana; S Avrameas; C Nauciel
Journal: Immunology Date: 1993-07 Impact factor: 7.397