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Literature DB >> 29249569

Hippo Signaling in the Immune System.

Yuchao Zhang¹, Haitao Zhang¹, Bin Zhao².

Abstract

Hippo signaling has a pivotal role in organ size control, tissue regeneration, and cancer. Recent studies have demonstrated critical functions of Hippo signaling in cancer immunity, innate immune responses against pathogens, and autoimmune diseases, refreshing our understanding of the implications of this pathway in the context of disease and therapy design.

Entities: Disease

Keywords: Hippo; TAZ; YAP; autoimmunity; cancer immunity; innate immunity

Mesh：

Substances：

Year: 2017 PMID： 29249569 DOI： 10.1016/j.tibs.2017.11.009

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

26 in total

1. Loss of VGLL4 suppresses tumor PD-L1 expression and immune evasion.

Authors: Ailing Wu; Qingzhe Wu; Yujie Deng; Yuning Liu; Jinqiu Lu; Liansheng Liu; Xiaoling Li; Cheng Liao; Bin Zhao; Hai Song
Journal: EMBO J Date: 2018-11-05 Impact factor: 11.598

2. Identification of an Autophagy-Related Signature Based on Whole Bone Marrow Sequencing for the Prognosis and Immune Microenvironment Characterization of Multiple Myeloma.

Authors: Licheng Li; Ting Chen; Jishi Wang; Mengxing Li; Qinshan Li
Journal: J Immunol Res Date: 2022-05-29 Impact factor: 4.493

3. Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis.

Authors: Dalton Dacus; Celeste Cotton; Tristan X McCallister; Nicholas A Wallace
Journal: J Virol Date: 2020-06-01 Impact factor: 5.103

4. YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3.

Authors: Dan Wang; Yening Zhang; Xueming Xu; Jianfeng Wu; Yue Peng; Jing Li; Ruiheng Luo; Lingmin Huang; Liping Liu; Songlin Yu; Ningjie Zhang; Ben Lu; Kai Zhao
Journal: Nat Commun Date: 2021-05-11 Impact factor: 14.919

5. The Hippo-YAP Pathway Regulates 3D Organ Formation and Homeostasis.

Authors: Erika Ishihara; Hiroshi Nishina
Journal: Cancers (Basel) Date: 2018-04-17 Impact factor: 6.639

6. Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression.

Authors: Ming-Xin Cao; Wei-Long Zhang; Xiang-Hua Yu; Jia-Shun Wu; Xin-Wei Qiao; Mei-Chang Huang; Ke Wang; Jing-Biao Wu; Ya-Jie Tang; Jian Jiang; Xin-Hua Liang; Ya-Ling Tang
Journal: J Exp Clin Cancer Res Date: 2020-06-03

Hippo Signaling in the Immune System.

1. Loss of VGLL4 suppresses tumor PD-L1 expression and immune evasion.

2. Identification of an Autophagy-Related Signature Based on Whole Bone Marrow Sequencing for the Prognosis and Immune Microenvironment Characterization of Multiple Myeloma.

3. Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis.

4. YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3.

5. The Hippo-YAP Pathway Regulates 3D Organ Formation and Homeostasis.

6. Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression.

7. Macropinosome formation by tent pole ruffling in macrophages.

8. YAP1 is a Prognostic Biomarker and Correlated with Immune Cell Infiltration in Pancreatic Cancer.

Review 9. YAP/TAZ Activation as a Target for Treating Metastatic Cancer.

Review 10. Hippo Pathway in Mammalian Adaptive Immune System.