Literature DB >> 29248434

Does my older cancer patient have cognitive impairment?

Jon Snaedal1.   

Abstract

Cancer and impaired cognition are both frequent conditions in old age and consequently coexist to certain degree. The prevalence of impaired cognition increases sharply after the age of 65 and the more advanced form of cognitive impairment; dementia, is exceeding 30% by the age of 85years. Adequate cognition is crucial for understanding important facts and for giving consent for intervention. There are many different stages of cognitive impairment, ranging from subjective cognitive impairment to severe dementia. The mildest stages of cognitive impairment are sometimes reversible but in more severe stages, there is brain damage of some kind, most frequently caused by neurodegenerative disorder such as Alzheimer's disease. Therefore, some kind of evaluation of cognition should be offered to all older individuals with cancer and in need for intervention. In this evaluation, information should also be sought from a close relative. In the earlier stages of cognitive impairment, the individual usually retains ability to give consent and understands information given but in later stages of dementia, a surrogate decision maker is needed. In milder stages of dementia, an individual evaluation is needed for decision of capability for consent. A specific diagnosis of a disorder such as Alzheimer's disease does not in itself preclude the individual from giving consent, the degree of cognitive impairment, impaired judgement and poor insight are more decisive in this regard. It is also important to know the difference of delirium, most often a time limited condition and dementia that usually is progressive.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Alzheimer's disease; Cancer; Cognitive impairment; Consent; Delirium; Dementia

Mesh:

Year:  2017        PMID: 29248434     DOI: 10.1016/j.jgo.2017.11.010

Source DB:  PubMed          Journal:  J Geriatr Oncol        ISSN: 1879-4068            Impact factor:   3.599


  5 in total

1.  Sleep Deprivation Induces Cognitive Impairment by Increasing Blood-Brain Barrier Permeability via CD44.

Authors:  Jing Sun; Jusheng Wu; Fuzhou Hua; Yong Chen; Fenfang Zhan; Guohai Xu
Journal:  Front Neurol       Date:  2020-11-27       Impact factor: 4.003

2.  Prevalence and Predictive Factors for Upfront Dose Reduction of the First Cycle of First-Line Chemotherapy in Older Adults with Metastatic Solid Cancer: Korean Cancer Study Group (KCSG) Multicenter Study.

Authors:  In Gyu Hwang; Minsuk Kwon; Jin Won Kim; Se Hyun Kim; Yun-Gyoo Lee; Jin Young Kim; Su-Jin Koh; Yoon Ho Ko; Seong Hoon Shin; Soojung Hong; Tae-Yong Kim; Sun Young Kim; Hyun Jung Kim; Hyo Jung Kim; Myung Ah Lee; Jung Hye Kwon; Yong Sang Hong; Kyung Hee Lee; Sung Hwa Bae; Dong-Hoe Koo; Jee Hyun Kim; In Sook Woo
Journal:  Cancers (Basel)       Date:  2021-01-18       Impact factor: 6.639

3.  A Prediction Model for Cognitive Impairment Risk in Colorectal Cancer after Chemotherapy Treatment.

Authors:  Shu-Ping Zhou; Su-Ding Fei; Hui-Hui Han; Jing-Jing Li; Shuang Yang; Chun-Yang Zhao
Journal:  Biomed Res Int       Date:  2021-02-20       Impact factor: 3.411

Review 4.  Opioid Therapy in Cancer Patients and Survivors at Risk of Addiction, Misuse or Complex Dependency.

Authors:  Joseph V Pergolizzi; Peter Magnusson; Paul J Christo; Jo Ann LeQuang; Frank Breve; Kailyn Mitchell; Giustino Varrassi
Journal:  Front Pain Res (Lausanne)       Date:  2021-11-16

Review 5.  The Impact of Cognitive Impairment on Treatment Toxicity, Treatment Completion, and Survival among Older Adults Receiving Chemotherapy: A Systematic Review.

Authors:  Schroder Sattar; Kristen Haase; Isabel Tejero; Cara Bradley; Caroline Mariano; Heather Kilgour; Ridhi Verma; Eitan Amir; Shabbir Alibhai
Journal:  Cancers (Basel)       Date:  2022-03-21       Impact factor: 6.639

  5 in total

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