| Literature DB >> 2924809 |
A K Karim1, T J Jacob, G M Thompson.
Abstract
A distinct disturbance to the structure of the lens epithelium was observed in cataract patients receiving steroid medication. Of those cataract patients receiving steroids, 83% exhibited a reticulated pattern of intercellular clefts compared to 5% in the control group. The reticulated pattern was shown to be due to the presence of gaps between the lateral borders of the epithelial cells by electron microscopy. A significant correlation between steroid therapy and epithelial disruption was demonstrated. The significance of such epithelial disruption to cataract formation is discussed.Entities:
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Year: 1989 PMID： 2924809 DOI： 10.1016/s0014-4835(89)80071-5
Source DB: PubMed Journal: Exp Eye Res ISSN： 0014-4835 Impact factor: 3.467