Literature DB >> 29247018

Value in Using CAR T Cells for DLBCL.

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Abstract

The phase II JULIET trial suggests that the CD19-targeting CAR T-cell therapy tisagenlecleucel produces durable responses in patients with relapsed and refractory diffuse large B-cell lymphoma. Three months after the therapy, 32% of the patients showed complete responses and 6% showed partial responses. After 6 months, those rates were 30% and 7%. ©2018 American Association for Cancer Research.

Entities:  

Year:  2017        PMID: 29247018     DOI: 10.1158/2159-8290.CD-NB2017-179

Source DB:  PubMed          Journal:  Cancer Discov        ISSN: 2159-8274            Impact factor:   39.397


  4 in total

1.  4-1BB enhancement of CAR T function requires NF-κB and TRAFs.

Authors:  Gongbo Li; Justin C Boucher; Hiroshi Kotani; Kyungho Park; Yongliang Zhang; Bishwas Shrestha; Xuefeng Wang; Lawrence Guan; Nolan Beatty; Daniel Abate-Daga; Marco L Davila
Journal:  JCI Insight       Date:  2018-09-20

2.  Naïve T-cell Deficits at Diagnosis and after Chemotherapy Impair Cell Therapy Potential in Pediatric Cancers.

Authors:  Rajat K Das; Lauren Vernau; Stephan A Grupp; David M Barrett
Journal:  Cancer Discov       Date:  2019-01-10       Impact factor: 39.397

Review 3.  Tisagenlecleucel for the treatment of B-cell acute lymphoblastic leukemia.

Authors:  Allison Barz Leahy; Caitlin W Elgarten; Stephan A Grupp; Shannon L Maude; David T Teachey
Journal:  Expert Rev Anticancer Ther       Date:  2018-10       Impact factor: 3.627

4.  Efficiency and safety of autologous chimeric antigen receptor T-cells therapy used for patients with lymphoma: A systematic review and meta-analysis.

Authors:  Genmao Cao; Lijian Lei; Xiaolin Zhu
Journal:  Medicine (Baltimore)       Date:  2019-10       Impact factor: 1.817

  4 in total

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