Literature DB >> 29246868

Clinical and demographic features of chronic progressive external ophthalmoplegia in a large adult-onset cohort.

Julia N Heighton1, Lauren I Brady1, Matthew C Newman1, Mark A Tarnopolsky2.   

Abstract

Chronic progressive external ophthalmoplegia (CPEO) is a common mitochondrial disease. We evaluated the impact of sex and smoking status upon knee extension strength and the phenotypic spectrum of disease in a large cohort of adult-onset CPEO patients (N=116) using retrospective chart analysis. The CPEO patients showed significantly lower knee extension strength as compared to the age- and sex-matched control population (-37%, P<0.05). Smoking also negatively impacted knee extension strength only in women with CPEO (-26%, P<0.05). We conclude that smoking and female sex interact negatively in CPEO patients.
Copyright © 2017 Elsevier B.V. and Mitochondria Research Society. All rights reserved.

Entities:  

Keywords:  Chronic progressive external ophthalmoplegia; Mitochondria; Phenotypic spectrum; Smoking; Strength

Mesh：

Year:  2017        PMID： 29246868     DOI： 10.1016/j.mito.2017.12.006

Source DB:  PubMed          Journal:  Mitochondrion        ISSN： 1567-7249            Impact factor:   4.160


  5 in total

Review 1.  Time to harmonize mitochondrial syndrome nomenclature and classification: A consensus from the North American Mitochondrial Disease Consortium (NAMDC).

Authors:  Valentina Emmanuele; Jaya Ganesh; Georgirene Vladutiu; Richard Haas; Douglas Kerr; Russell P Saneto; Bruce H Cohen; Johan L K Van Hove; Fernando Scaglia; Charles Hoppel; Xiomara Q Rosales; Emanuele Barca; Richard Buchsbaum; John L Thompson; Salvatore DiMauro; Michio Hirano
Journal:  Mol Genet Metab       Date:  2022-05-13       Impact factor: 4.204

2.  Primary mitochondrial myopathy: Clinical features and outcome measures in 118 cases from Italy.

Authors:  Vincenzo Montano; Francesco Gruosso; Valerio Carelli; Giacomo Pietro Comi; Massimiliano Filosto; Costanza Lamperti; Tiziana Mongini; Olimpia Musumeci; Serenella Servidei; Paola Tonin; Antonio Toscano; Angela Modenese; Guido Primiano; Maria Lucia Valentino; Sara Bortolani; Silvia Marchet; Megi Meneri; Graziana Tavilla; Gabriele Siciliano; Michelangelo Mancuso
Journal:  Neurol Genet       Date:  2020-10-20

Review 3.  Use of Next-Generation Sequencing for Identifying Mitochondrial Disorders.

Authors:  Shafi Mahmud; Suvro Biswas; Shamima Afrose; Mohasana Akter Mita; Md Robiul Hasan; Mst Sharmin Sultana Shimu; Gobindo Kumar Paul; Sanghyun Chung; Md Abu Saleh; Sultan Alshehri; Momammed M Ghoneim; Maha Alruwaily; Bonglee Kim
Journal:  Curr Issues Mol Biol       Date:  2022-02-27       Impact factor: 2.976

4.  Progressive External Ophthalmoplegia in Polish Patients-From Clinical Evaluation to Genetic Confirmation.

Authors:  Biruta Kierdaszuk; Magdalena Kaliszewska; Joanna Rusecka; Joanna Kosińska; Ewa Bartnik; Katarzyna Tońska; Anna M Kamińska; Anna Kostera-Pruszczyk
Journal:  Genes (Basel)       Date:  2020-12-31       Impact factor: 4.096

5.  Prevalence and health care costs of mitochondrial disease in Ontario, Canada: A population-based cohort study.

Authors:  Emmalin Buajitti; Laura C Rosella; Ersi Zabzuni; L Trevor Young; Ana C Andreazza
Journal:  PLoS One       Date:  2022-04-08       Impact factor: 3.240
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.