Anuli N Nwaohiri1, Jennifer H Tang2, Frank Stanczyk3, Lameck Chinula2, Stacey Hurst1, Nicole L Davis1, Gerald Tegha2, Lisa Haddad4, Athena P Kourtis5. 1. Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. 2. University of North Carolina Project, Lilongwe, Malawi. 3. Department of Obstetrics and Gynecology, University of Southern California Keck School of Medicine. 4. Emory University, Department of Obstetrics & Gynecology, Atlanta, GA, USA. 5. Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: apk3@cdc.gov.
Abstract
OBJECTIVE: The objective was to assess the extent of concordance between self-reported contraceptive use and the presence of contraceptive progestins in serum. STUDY DESIGN: We evaluated self-reported contraceptive use by using radioimmunoassay to examine baseline serum levels of medroxyprogesterone acetate (MPA) and levonorgestrel (LNG) among 97 Malawian women enrolling in a contraceptive trial. RESULTS:Twelve percent (12/97) of study participants who reported no hormonal contraceptive use in the previous 6months had either MPA or LNG detected in their serum. CONCLUSIONS: The observed discordance between self-report and detection of exogenous hormones in serum indicates that caution is warranted when drawing conclusions based on self-reported contraceptive use. Published by Elsevier Inc.
RCT Entities:
OBJECTIVE: The objective was to assess the extent of concordance between self-reported contraceptive use and the presence of contraceptive progestins in serum. STUDY DESIGN: We evaluated self-reported contraceptive use by using radioimmunoassay to examine baseline serum levels of medroxyprogesterone acetate (MPA) and levonorgestrel (LNG) among 97 Malawian women enrolling in a contraceptive trial. RESULTS: Twelve percent (12/97) of study participants who reported no hormonal contraceptive use in the previous 6months had either MPA or LNG detected in their serum. CONCLUSIONS: The observed discordance between self-report and detection of exogenous hormones in serum indicates that caution is warranted when drawing conclusions based on self-reported contraceptive use. Published by Elsevier Inc.
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