| Literature DB >> 29243874 |
André B Rietman1,2, Thijs van der Vaart1,3,4, Ellen Plasschaert5, Bethany A Nicholson1, Rianne Oostenbrink1,3, Lianne C Krab1, Mie-Jef Descheemaeker5, Marie-Claire Y de Wit1,6, Henriëtte A Moll1,3, Eric Legius5, Pieter F A de Nijs1,2.
Abstract
To assess emotional and behavioral problems in children and adolescents with neurofibromatosis type 1,parents of 183 individuals aged 10.8 ± 3.1 years (range 6-17) completed the Child Behavior Checklist (CBCL). Also, 173 teachers completed the Teacher's Report Form (TRF), and 88 adolescents (children from 11 to 17 years) completed the Youth Self-Report (YSR). According to parental ratings, 32% scored in the clinical range (above the 90th percentile). This percentage was much lower when rated by teachers or adolescents themselves. Scores from all informants on scales for Somatic complaints, Social problems, and Attention problems were significantly different from normative scores. Attentional problems were associated with lower verbal IQ, male gender, younger age, and ADHD-symptoms. Disease-related factors did not predict behavioral problems scores. Substantial emotional and behavioral problems were reported by parents, teachers, and to a lesser extent by adolescents with NF1 themselves. Possibly, a positive illusory bias affects the observation of behavioral problems by adolescents with NF1.Entities:
Keywords: emotional and behavioral problems; neurofibromatosis type 1; parent and teacher report; positive illusory bia; self-report
Mesh：
Year: 2017 PMID： 29243874 DOI： 10.1002/ajmg.b.32612
Source DB: PubMed Journal: Am J Med Genet B Neuropsychiatr Genet ISSN： 1552-4841 Impact factor: 3.568