Literature DB >> 29243188

Current management of lipoblastoma.

Emmanuelle Séguier-Lipszyc1, Artur Baazov2, Suzanna Fichman3, Shifra Ash4, Enrique Freud2.   

Abstract

Lipoblastoma is a rare and benign tumor arising from embryonal fat cells. It is generally diagnosed in children younger than 3 years of age and can occur in the extremities or on the trunk. We present our series of 10 children with lipoblastoma treated at Schneider Children's Medical Center of Israel between 2011 and 2016. Six boys and four girls underwent tumor resection at a median age of 2 years and 3 months (range 5 months to 5.6 years). Locations were trunk (6), groin (2), perineum (1), and omentum (1). Follow up ranges from 1 to 5 years. Two patients had a local recurrence and required a second resection 2 years (perineal) and 6 years (trunk) after the first surgery without further recurrence at 1.9 and 2.9 years, respectively.
CONCLUSION: Higher awareness of lipoblastoma enables optimal imaging strategies and resection. Long follow up is required due to local recurrences. The treatment of choice consists of complete, but non mutilating surgical resection. What is Known: • Lipoblastoma is a rare benign tumor of fatty tissue affecting children • Treatment consists of surgical resection What is New: • MRI is the modality of choice for follow up • Ten-year long-term follow up is required due to late recurrence.

Entities:  

Keywords:  Children; Lipoblastoma; Liposarcoma; Surgical resection

Mesh:

Year:  2017        PMID: 29243188     DOI: 10.1007/s00431-017-3059-9

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  17 in total

1.  Lipoblastomatosis: a tumor of fetal fat different from hibernoma; report of a case, with observations on the embryogenesis of human adipose tissue.

Authors:  F VELLIOS; J BAEZ; H B SHUMACKER
Journal:  Am J Pathol       Date:  1958 Nov-Dec       Impact factor: 4.307

2.  Lipoblastoma/lipoblastomatosis: a clinicopathologic study of 16 cases in Taiwan.

Authors:  Shih-Ming Jung; Pei-Yeh Chang; Chih-Cheng Luo; Chen-Sheng Huang; Jin-Yao Lai; Chuen Hsueh
Journal:  Pediatr Surg Int       Date:  2005-10-21       Impact factor: 1.827

3.  Benign lipoblastomatosis. An analysis of 35 cases.

Authors:  E B Chung; F M Enzinger
Journal:  Cancer       Date:  1973-08       Impact factor: 6.860

4.  Lipoblastoma: clinical features, treatment, and outcome.

Authors:  Kenneth Y Y Kok; P U Telisinghe
Journal:  World J Surg       Date:  2010-07       Impact factor: 3.352

5.  Lipoblastoma/lipoblastomatosis: a clinicopathologic study of 25 tumors.

Authors:  M H Collins; J Chatten
Journal:  Am J Surg Pathol       Date:  1997-10       Impact factor: 6.394

Review 6.  Two young girls with lipoblastoma and a review of the literature.

Authors:  Anna L Chien; David H Song; Sarah L Stein
Journal:  Pediatr Dermatol       Date:  2006 Mar-Apr       Impact factor: 1.588

7.  Cytological features of lipoblastoma: a report of three cases.

Authors:  V Veronika Kloboves-Prevodnik; Marija Us-Krasovec; N Gale; Janez Lamovec
Journal:  Diagn Cytopathol       Date:  2005-09       Impact factor: 1.582

8.  Lipoblastoma in infancy and childhood.

Authors:  J F Jimenez
Journal:  J Surg Oncol       Date:  1986-08       Impact factor: 3.454

9.  Lipoblastoma in infants and children.

Authors:  G Stringel; B Shandling; K Mancer; S H Ein
Journal:  J Pediatr Surg       Date:  1982-06       Impact factor: 2.545

10.  Giant mesenteric lipoblastoma in a 4-year-old child.

Authors:  Xiao Bing Tang; Tao Zhang; Yu Zuo Bai; Wei Lin Wang
Journal:  J Pediatr Surg       Date:  2009-04       Impact factor: 2.545

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  6 in total

1.  Follow-up outcomes of pediatric patients who underwent surgical resection for lipoblastomas or lipoblastomatosis: a single-institution experience with a systematic review and meta-analysis.

Authors:  Dyda Dao; Anna J Najor; Philip Y Sun; Forough Farrokhyar; Christopher R Moir; Michael B Ishitani
Journal:  Pediatr Surg Int       Date:  2020-01-14       Impact factor: 1.827

2.  Lipoblastomas and liposarcomas in paediatric patients: A case series.

Authors:  Joyce J L H McRae; Asra Hashmi; Andrei Radulescu; Cody S Carter; Faraz A Khan
Journal:  J Int Med Res       Date:  2021-03       Impact factor: 1.671

3.  Imaging features of Lipoblastoma.

Authors:  Farida Mohsin Ambusaidi; Latifa Al-Mammari; Yahya Al-Brashdi; Ruqaiya Mubarak Al-Shamsi
Journal:  Int J Pediatr Adolesc Med       Date:  2021-06-03

4.  Primary liposarcoma of the omentum: A case report.

Authors:  Ying Gao; Yujie Qin; Yingchao Wang; Xiaoling Quan; Xiaoyi Wei; Jiaxi Yao
Journal:  Medicine (Baltimore)       Date:  2022-01-07       Impact factor: 1.889

Review 5.  Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview.

Authors:  Eline Ameloot; Fleur Cordier; Jo Van Dorpe; David Creytens
Journal:  J Clin Med       Date:  2022-03-31       Impact factor: 4.241

6.  Shoulder Lipoblastoma in a 2-Year-Old Boy Case Report and Literature Review.

Authors:  Abdulaziz Adnan Al-Tammar; Abdullah Al-Faraj; Wael T Abodief; Jarrah Abughaith; Aliaa Khaja
Journal:  J Orthop Case Rep       Date:  2021-12
  6 in total

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