Literature DB >> 29242982

[Iron, a "miralcle cure" for chronic cardiac insufficiency?]

Katrin Singler1,2.   

Abstract

Anemia and chronic heart failure are frequent comorbidities in geriatric patients. In approximately one third of older adults the cause of the anemia is an iron, vitamin B12 and/or folate deficiency and in another third a chronic inflammatory process is present. In the case of iron deficiency a differentiation must be made between the absolute and functional forms. Although in functional iron deficiency ferritin, as a parameter of iron metabolism, is within the normal range or can even be higher, an iron-deficient erythropoiesis is present. In cardiac insufficiency a chronic inflammatory process is assumed. According to the recent guidelines of the Deutsche Gesellschaft für Kardiologie (DGK, German Cardiac Society) and European Society of Cardiology (ESC) a routine contol of the iron status should be performed and, if necessary, initiation of adequate supplementation is recommended.

Entities:  

Keywords:  Anemia; Ferric carboxymaltose; Immunogenicity; Iron deficiency; Transferrin saturation

Mesh:

Substances:

Year:  2017        PMID: 29242982     DOI: 10.1007/s00391-017-1357-5

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  19 in total

1.  Anemia in old age is associated with increased mortality and hospitalization.

Authors:  Brenda W J H Penninx; Marco Pahor; Richard C Woodman; Jack M Guralnik
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2006-05       Impact factor: 6.053

Review 2.  Epidemiology of anemia in older adults.

Authors:  Kushang V Patel
Journal:  Semin Hematol       Date:  2008-10       Impact factor: 3.851

Review 3.  Iron uptake and metabolism in the new millennium.

Authors:  Louise L Dunn; Yohan Suryo Rahmanto; Des R Richardson
Journal:  Trends Cell Biol       Date:  2006-12-27       Impact factor: 20.808

4.  Iron deficiency: an ominous sign in patients with systolic chronic heart failure.

Authors:  Ewa A Jankowska; Piotr Rozentryt; Agnieszka Witkowska; Jolanta Nowak; Oliver Hartmann; Beata Ponikowska; Ludmila Borodulin-Nadzieja; Waldemar Banasiak; Lech Polonski; Gerasimos Filippatos; John J V McMurray; Stefan D Anker; Piotr Ponikowski
Journal:  Eur Heart J       Date:  2010-06-21       Impact factor: 29.983

5.  Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein.

Authors:  Elizabeta Nemeth; Erika V Valore; Mary Territo; Gary Schiller; Alan Lichtenstein; Tomas Ganz
Journal:  Blood       Date:  2002-11-14       Impact factor: 22.113

6.  [Serum hepcidin levels in geriatric patients with iron deficiency anemia or anemia of chronic diseases].

Authors:  G Röhrig; G Rappl; B Vahldick; I Kaul; R J Schulz
Journal:  Z Gerontol Geriatr       Date:  2014-01       Impact factor: 1.281

7.  Risk factors associated with hospitalization for unintentional falls: Wisconsin hospital discharge data for patients aged 65 and over.

Authors:  Clare E Guse; Rebecca Porinsky
Journal:  WMJ       Date:  2003

8.  Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia.

Authors:  Jack M Guralnik; Richard S Eisenstaedt; Luigi Ferrucci; Harvey G Klein; Richard C Woodman
Journal:  Blood       Date:  2004-07-06       Impact factor: 22.113

Review 9.  The Global Burden of Anemia.

Authors:  Nicholas J Kassebaum
Journal:  Hematol Oncol Clin North Am       Date:  2016-04       Impact factor: 3.722

Review 10.  Prevalence of anaemia in older persons: systematic review.

Authors:  Helen Gaskell; Sheena Derry; R Andrew Moore; Henry J McQuay
Journal:  BMC Geriatr       Date:  2008-01-14       Impact factor: 3.921

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