Literature DB >> 29242712

Corrigendum: Conditional Knockout of Cav2.1 Disrupts the Accuracy of Spatial Recognition of CA1 Place Cells and Spatial/Contextual Recognition Behavior.

Dahee Jung1,2, Yu J Hwang3, Hoon Ryu3,4, Masanobu Kano5, Kenji Sakimura6, Jeiwon Cho1,2.   

Abstract

[This corrects the article on p. 214 in vol. 10, PMID: 27857685.].

Entities:  

Keywords:  P/Q type calcium channels; burst; hippocampus; learning and memory; place cell

Year:  2017        PMID: 29242712      PMCID: PMC5727092          DOI: 10.3389/fnbeh.2017.00242

Source DB:  PubMed          Journal:  Front Behav Neurosci        ISSN: 1662-5153            Impact factor:   3.558


In the original article, there were errors on citation. The statement on the mouse line from Mallmann's paper (Mallmann et al., 2013) was found to be irrelevant to our work and conclusion; thus the statement “Although a recent study circumvented the lethal phenotype by using the Cre-loxP system under the control of the NEX promoter to delete Cav2.1 in the neocortex, the mice still displayed substantial emotional impairments including anxiety and seizure. These affective changes observed in this transgenic mice line may have interfered with their performance in learning and memory tasks, therefore, results could be inconclusive in its attempt to identify the role of Cav2.1 in spatial learning and memory and hippocampal place cell activity” in the introduction section should be eliminated from this article. In addition, the citation in the discussion section was misplaced at the end of statement to mislead information on specific subtype of calcium channels as following “Considering the previous studies, it is possible for dendritic Ca2+ influx via Cav2.1 to play a role in learning and memory in collaboration with NMDA channels by modulating bursting in that NMDA have been known to be involved in learning and memory both in vitro and in vivo studies (Cui et al., 2004; Moosmang et al., 2005; Place et al., 2012).” Therefore, the citation should be replaced to the appropriate place “Considering the previous studies (Cui et al., 2004; Moosmang et al., 2005; Place et al., 2012).” The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
  4 in total

1.  Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.

Authors:  Zhenzhong Cui; Huimin Wang; Yuansheng Tan; Kimberly A Zaia; Shuqin Zhang; Joe Z Tsien
Journal:  Neuron       Date:  2004-03-04       Impact factor: 17.173

2.  NMDA signaling in CA1 mediates selectively the spatial component of episodic memory.

Authors:  Ryan Place; Christy Lykken; Zachery Beer; Junghyup Suh; Thomas J McHugh; Susumu Tonegawa; Howard Eichenbaum; Magdalena M Sauvage
Journal:  Learn Mem       Date:  2012-03-14       Impact factor: 2.460

3.  Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.

Authors:  Sven Moosmang; Nicole Haider; Norbert Klugbauer; Helmuth Adelsberger; Nicolas Langwieser; Jochen Müller; Michael Stiess; Else Marais; Verena Schulla; Lubica Lacinova; Sandra Goebbels; Klaus-Armin Nave; Daniel R Storm; Franz Hofmann; Thomas Kleppisch
Journal:  J Neurosci       Date:  2005-10-26       Impact factor: 6.167

4.  Ablation of Ca(V)2.1 voltage-gated Ca²⁺ channels in mouse forebrain generates multiple cognitive impairments.

Authors:  Robert Theodor Mallmann; Claudio Elgueta; Faten Sleman; Jan Castonguay; Thomas Wilmes; Arn van den Maagdenberg; Norbert Klugbauer
Journal:  PLoS One       Date:  2013-10-31       Impact factor: 3.240

  4 in total

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