Literature DB >> 2924137

Regional calcium accumulation and kainic acid (KA)-induced limbic seizure status in rats.

S Tanaka1, K Sako, T Tanaka, Y Yonemasu.   

Abstract

The sites of calcium accumulation were studied by 45Ca autoradiography during kainic acid (KA)-induced limbic seizure in rats. Two hours after KA injection into unilateral amygdala, calcium accumulated in CA3 of the hippocampus, lateral septal nucleus and thalamic reticular nucleus on KA-injected side. Those sites coincided with the sites where neuronal cell damage appeared 4 h after KA injection. These results suggested that regional calcium accumulation might be responsible for neuronal cell loss induced by seizures.

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Year:  1989        PMID： 2924137     DOI： 10.1016/0006-8993(89)91522-9

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  3 in total

1.  Seizure-related changes in the glutamate R2 and R5 receptor genes expression in the rat hippocampal formation.

Authors:  W Lasoń; J Turchan; B Przewłocka; D Labuz; J Mika; R Przewłocki
Journal:  J Neural Transm (Vienna)       Date:  1997       Impact factor: 3.575

2.  Cliniconeuropathologic findings of familial frontal lobe epilepsy in Shetland sheepdogs.

Authors:  T Morita; A Shimada; T Takeuchi; Y Hikasa; M Sawada; S Ohiwa; M Takahashi; N Kubo; T Shibahara; H Miyata; E Ohama
Journal:  Can J Vet Res       Date:  2002-01       Impact factor: 1.310

3.  Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20.

Authors:  Gusheng Wu; Zi-Hua Lu; Xin Xie; Robert W Ledeen
Journal:  Glycoconj J       Date:  2004       Impact factor: 2.916
  3 in total

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