Literature DB >> 2924117

Neuronal loss in lumbar dorsal root ganglia after proximal compared to distal sciatic nerve resection: a quantitative study in the rat.

J Ygge1.   

Abstract

The effects of unilateral sciatic nerve resections at proximal (thigh) or distal (proximal calf) locations on L4-L6 dorsal root ganglion (DRG) neuronal numbers have been studied in adult rats. Proximal nerve resection gave rise to a mean DRG neuronal loss of 27%, whereas in distal lesions a mean cell loss of 7% was found. This difference in cell loss between proximal and distal sciatic nerve resections is highly significant (P less than 0.001).

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Year:  1989        PMID： 2924117     DOI： 10.1016/0006-8993(89)91497-2

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  3 in total

1.  Peripheral axotomy induces long-term c-Jun amino-terminal kinase-1 activation and activator protein-1 binding activity by c-Jun and junD in adult rat dorsal root ganglia In vivo.

Authors:  A M Kenney; J D Kocsis
Journal:  J Neurosci       Date:  1998-02-15       Impact factor: 6.167

2.  Protective effect of interleukin-1beta on motor neurons after sciatic nerve injury in rats.

Authors:  Yuxiong Weng; Bharat Khatri; Guangxiang Hong; Fabin Wang; Zhenbin Chen; Qishun Huang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2004

3.  Local Riluzole Release from a Thermosensitive Hydrogel Rescues Injured Motoneurons through Nerve Root Stumps in a Brachial Plexus Injury Rat Model.

Authors:  Jintao Fang; Liang Li; Hong Zhai; Bengang Qin; Daping Quan; Enxian Shi; Menghai Zhu; Jiantao Yang; Xiaolin Liu; Liqiang Gu
Journal:  Neurochem Res       Date:  2020-09-28       Impact factor: 3.996
  3 in total

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