Literature DB >> 29241081

Does misuse lead to a disorder? The misuse of prescription tranquilizer and sedative medications and subsequent substance use disorders in a U.S. longitudinal sample.

C J Boyd1, B West2, S E McCabe3.   

Abstract

OBJECTIVES: We used two waves of National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) data and examined whether the misuse of prescription tranquilizers or sedatives at Wave 1 was associated with either continued misuse, tranquilizer/sedative use disorder, or other substance use disorder (SUD) at Wave 2.
METHODS: Prospective data were analyzed from structured diagnostic interviews using the Alcohol Use disorders and Associated Disabilities Interview Schedule: DSM-IV Version (AUDADIS-DSM-IV). A nationally representative sample of 34,653 of U.S. adults, 18years or older at Wave 1 (2001-2002), were re-interviewed at Wave 2 (2004-2005). After applying the survey weights, the sample represented a population that was 52% female, 71% White, 12% Hispanic, 11% African American, 4% Asian and 2% Native American or other.
RESULTS: An estimated 79% of adults who engaged in tranquilizer or sedative misuse at Wave 1 had stopped using these drugs at Wave 2. Only a small percentage (4.3%) of misusers at Wave 1 had a tranquilizer or sedative use disorder at Wave 2. However, 45% (45.0%) of misusers at Wave 1 had at least one other SUD at Wave 2. Among those in remission from a sedative or tranquilizer use disorder at Wave 1, 4.8% had a tranquilizer or sedative use disorder while 34.7% had at least one other SUD at Wave 2.
CONCLUSIONS: Most adults who engaged in the misuse of prescription tranquilizers or sedatives ceased using within 3years; however, their prior misuse was associated with higher prevalence of having a SUD three years later.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Drug use disorders; Prescription drug misuse; Sedative medication misuse; Substance abuse; Tranquilizer medication misuse

Mesh:

Substances:

Year:  2017        PMID: 29241081      PMCID: PMC5884701          DOI: 10.1016/j.addbeh.2017.11.042

Source DB:  PubMed          Journal:  Addict Behav        ISSN: 0306-4603            Impact factor:   3.913


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4.  Concordance of DSM-IV alcohol and drug use disorder criteria and diagnoses as measured by AUDADIS-ADR, CIDI and SCAN.

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5.  The role of a prescription in anxiety medication use, abuse, and dependence.

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7.  Non-medical use of prescription analgesics: a three-year national longitudinal study.

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8.  Probability and predictors of remission from life-time prescription drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

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9.  The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample.

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10.  Epidemiology of DSM-5 Drug Use Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions-III.

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  11 in total

1.  Prescription tranquilizer/sedative misuse prevalence and correlates across age cohorts in the US.

Authors:  Ty S Schepis; Christian J Teter; Linda Simoni-Wastila; Sean Esteban McCabe
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2.  The epidemiology of benzodiazepine misuse: A systematic review.

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3.  Adolescent and Parent Management of Controlled Prescription Medications.

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4.  Age-specific risk of substance use disorders associated with controlled medication use and misuse subtypes in the United States.

Authors:  Sean Esteban McCabe; Timothy E Wilens; Carol J Boyd; Kao-Ping Chua; Terri Voepel-Lewis; Ty S Schepis
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5.  Prescription Tranquilizer/Sedative Misuse Motives Across the US Population.

Authors:  Ty S Schepis; Linda Wastila; Sean Esteban McCabe
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6.  Sedative/Tranquilizer Misuse is Associated With Alcohol and Illicit Drug Problems, Mental Health Issues, and Impulsivity and Compulsivity in University Students.

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7.  Nonmedical prescription psychiatric drug use and the darknet: A cryptomarket analysis.

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Review 9.  Prescription Drug Misuse: Taking a Lifespan Perspective.

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10.  Gender Differences in Predictors of Self-Medication with Tranquillizers and Sleeping Pills: Results of the Population-Based Study in Serbia.

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