| Literature DB >> 2923845 |
L Bernstein1, M C Pike, R A Lobo, R H Depue, R K Ross, B E Henderson.
Abstract
We have examined serum levels of oestradiol (E2), sex-hormone binding globulin (SHBG) and human chorionic gonadotrophin (hCG) during early pregnancy in relation to smoking status at the time of sampling in a series of 147 women. Smoking was associated with significantly depressed serum levels of E2, SHBG and hCG: in smokers, E2 levels were on average 17.6% lower (P = 0.037), SHBG levels were 12.4% lower (P = 0.15), and hCG levels were 21.5% lower (P = 0.044). There appeared to be a steady decline in these values with increasing cigarette consumption. These lower hormone levels in smokers may explain certain adverse effects of smoking in pregnancy.Entities:
Keywords: Americas; Behavior; Biology; Body Weight; Demographic Factors; Developed Countries; Endocrine System; Estradiol--analysis; Estrogens; Examinations And Diagnoses; Gonadotropins; Gonadotropins, Chorionic--analysis; Hormones; Laboratory Examinations And Diagnoses; North America; Northern America; Physiology; Population; Population Characteristics; Pregnancy; Reproduction; Smoking--side effects; United States
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Year: 1989 PMID： 2923845 DOI： 10.1111/j.1471-0528.1989.tb01582.x
Source DB: PubMed Journal: Br J Obstet Gynaecol ISSN： 0306-5456