Literature DB >> 2923421

Age: an important factor in Barrett's oesophagus.

G A Khoury1, J Bolton.   

Abstract

Thirty-one patients with a columnar lined oesophagus were studied. Half the patients were aged 70 years or over and only four patients were under 60 years of age at presentation. More than two-thirds of patients presented with a complication. Comparison by age showed a significant difference (P = 0.006) between the nine patients with uncomplicated Barrett's oesophagus (median age 64 years, range 28-79 years) and the 22 presenting with a complication (median age 75 years, range 36-89 years). This finding supports the view that the condition is acquired and that complications occur after injury resulting from prolonged reflux. Five patients (16%) had a carcinoma. Of the remaining 26 patients only seven (27%) underwent an antireflux procedure. Old age, associated medical problems and the effective control of symptoms by medical management (drugs and dilatation), reduced the need for surgery in this elderly population.

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Mesh:

Year:  1989        PMID: 2923421      PMCID: PMC2498872     

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  5 in total

1.  Barrett's oesophagus: pH profile.

Authors:  P Gillen; P Keeling; P J Byrne; T P Hennessy
Journal:  Br J Surg       Date:  1987-09       Impact factor: 6.939

Review 2.  Barrett's esophagus.

Authors:  S J Spechler; R K Goyal
Journal:  N Engl J Med       Date:  1986-08-07       Impact factor: 91.245

3.  Experimental columnar metaplasia in the canine oesophagus.

Authors:  P Gillen; P Keeling; P J Byrne; A B West; T P Hennessy
Journal:  Br J Surg       Date:  1988-02       Impact factor: 6.939

4.  Regression of columnar esophageal (Barrett's) epithelium after anti-reflux surgery.

Authors:  D L Brand; J T Ylvisaker; M Gelfand; C E Pope
Journal:  N Engl J Med       Date:  1980-04-10       Impact factor: 91.245

5.  Columnar-lined lower esophagus: an acquired lesion with malignant predisposition. Report on 140 cases of Barrett's esophagus with 12 adenocarcinomas.

Authors:  A P Naef; M Savary; L Ozzello
Journal:  J Thorac Cardiovasc Surg       Date:  1975-11       Impact factor: 5.209

  5 in total
  1 in total

Review 1.  Epidemiology of gastro-esophageal reflux disease.

Authors:  P J Howard; R C Heading
Journal:  World J Surg       Date:  1992 Mar-Apr       Impact factor: 3.352

  1 in total

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