Goele Jans1,2, Christophe Matthys3,4, Annick Bogaerts5,6,7, Lieveke Ameye5, Frank Delaere8, Kristien Roelens9, Anne Loccufier10, Hilde Logghe11, Ben De Becker12, Johan Verhaeghe5,13, Roland Devlieger5,12,13. 1. Department of Development and Regeneration, KU Leuven, Herestraat 49, 3000, Leuven, Limburg, Belgium. Goele.jans@ucll.be. 2. Faculty of Health and Social Work, Research Unit Healthy Living, UC Leuven-Limburg, Leuven, Belgium. Goele.jans@ucll.be. 3. Department of Clinical and Experimental Medicine, KU Leuven, Leuven, Belgium. 4. Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium. 5. Department of Development and Regeneration, KU Leuven, Herestraat 49, 3000, Leuven, Limburg, Belgium. 6. Faculty of Health and Social Work, Research Unit Healthy Living, UC Leuven-Limburg, Leuven, Belgium. 7. Faculty of Medicine and Health Sciences, Centre for Research and Innovation in Care (CRIC), University of Antwerp, Antwerp, Belgium. 8. Faculty of Health and Social Work, Nutrition and Dietetics, UC Leuven-Limburg, Leuven, Belgium. 9. Department of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium. 10. Department of Obstetrics and Gynecology, AZ St-Jan Bruges, Bruges, Belgium. 11. Department of Obstetrics and Gynecology, AZ St-Lucas, Bruges, Belgium. 12. Department of Obstetrics and Gynecology, AZ St. Augustinus Wilrijk, Wilrijk, Belgium. 13. Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium.
Abstract
BACKGROUND: Anxiety and depression levels are higher in obese compared to those in normal weight pregnant women. The aims of this study are to examine anxiety and depression in pregnancy following bariatric surgery and to compare with obese pregnant controls considering the dietary intake of polyunsaturated fatty acids (PUFA), folate, and vitamin B12. METHODS: Anxiety (State-Trait Anxiety Inventory) and depression (Edinburgh Postnatal Depression Scale) were examined in the first (T1) and third (T3) pregnancy trimester in 54 women with bariatric surgery and 25 obese. T1 and T3 dietary intake of PUFA, folate, and vitamin B12 intake was assessed using a 3-day food record. Mixed models with a compound symmetry covariance structure and regression models were applied. RESULTS: About half of the women with surgery had high state and trait anxiety scores (≥ 40), which did not significantly change during pregnancy. Every 10-kg postoperative weight loss was associated with an increase in T1 state and trait anxiety with respectively 2.7 and 2.3 points. A smoking woman had a 8.6-point higher state anxiety score than a non-smoking woman in T1. In T3, every additional hour of sleep was associated with a decrease in trait anxiety score with 1.59 points. Anxiety and depression scores were not associated with and could not be explained by inadequate PUFAs, folate, and vitamin B12 intakes. Anxiety scores were higher following surgery than those in untreated obesity at both time points. CONCLUSION: Pregnancy following bariatric surgery induces high levels of anxiety that are not associated with an inadequate maternal diet.
BACKGROUND:Anxiety and depression levels are higher in obese compared to those in normal weight pregnant women. The aims of this study are to examine anxiety and depression in pregnancy following bariatric surgery and to compare with obese pregnant controls considering the dietary intake of polyunsaturated fatty acids (PUFA), folate, and vitamin B12. METHODS:Anxiety (State-Trait Anxiety Inventory) and depression (Edinburgh Postnatal Depression Scale) were examined in the first (T1) and third (T3) pregnancy trimester in 54 women with bariatric surgery and 25 obese. T1 and T3 dietary intake of PUFA, folate, and vitamin B12 intake was assessed using a 3-day food record. Mixed models with a compound symmetry covariance structure and regression models were applied. RESULTS: About half of the women with surgery had high state and trait anxiety scores (≥ 40), which did not significantly change during pregnancy. Every 10-kg postoperative weight loss was associated with an increase in T1 state and trait anxiety with respectively 2.7 and 2.3 points. A smoking woman had a 8.6-point higher state anxiety score than a non-smoking woman in T1. In T3, every additional hour of sleep was associated with a decrease in trait anxiety score with 1.59 points. Anxiety and depression scores were not associated with and could not be explained by inadequate PUFAs, folate, and vitamin B12 intakes. Anxiety scores were higher following surgery than those in untreated obesity at both time points. CONCLUSION: Pregnancy following bariatric surgery induces high levels of anxiety that are not associated with an inadequate maternal diet.
Authors: Goele Jans; Christophe Matthys; Sarah Bel; Lieveke Ameye; Matthias Lannoo; Bart Van der Schueren; Bruno Dillemans; Luc Lemmens; Jean-Pierre Saey; Yves van Nieuwenhove; Pascale Grandjean; Ben De Becker; Hilde Logghe; Marc Coppens; Kristien Roelens; Anne Loccufier; Johan Verhaeghe; Roland Devlieger Journal: BMC Pregnancy Childbirth Date: 2016-07-29 Impact factor: 3.007