Agrima Vasudeva1, Dakshita Joy Sinha2, Shashi Prabha Tyagi2, Narendra Nath Singh3, Paridhi Garg4, Deepti Upadhyay5. 1. Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh 244001, India. Electronic address: dr.agrima.vasudeva@gmail.com. 2. Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh 244001, India. 3. Department of Oral Pathology and Microbiology, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh 244001, India. 4. Noida, Uttar Pradesh, India. 5. Department of Oral Pathology and Microbiology, Buddha Institute of Dental Sciences, Patna, Bihar, India.
Abstract
AIM: This in vitro study was conducted to evaluate the disinfection of dentinal tubules using 2% Chlorhexidine gel, Honey, Aloe vera gel, Curcuma longa, Propolis gel and Calcium hydroxide against Enterococcus faecalis. MATERIALS AND METHOD: Two hundred and ten human mandibular first premolars were infected with Enterococcus faecalis for 21 days. Samples were divided into 7 groups. Group I- Saline (negative control), Group II- 2% Chlorhexidine gel(CHX), Group III- honey, Group IV- Aloe vera gel, Group V- 20% Curcuma longa gel, Group VI- Propolis gel and Group VII -Calcium hydroxide (CH). At the end of 1, 3 and 5 days, the antimicrobial efficacy of medicaments against E.faecalis was assessed at the depths of 200µm and 400µm. RESULTS: 2% Chlorhexidine gel was most effective followed by Propolis and Curcuma longa. CONCLUSION: 2% Chlorhexidine gel gave the best results. Among the herbal extracts Propolis and Curcuma longa hold a promising future but to implement their use as sole intracanal medicaments clinically, further in vivo and long term studies are warranted.
AIM: This in vitro study was conducted to evaluate the disinfection of dentinal tubules using 2% Chlorhexidine gel, Honey, Aloe vera gel, Curcuma longa, Propolis gel and Calcium hydroxide against Enterococcus faecalis. MATERIALS AND METHOD: Two hundred and ten human mandibular first premolars were infected with Enterococcus faecalis for 21 days. Samples were divided into 7 groups. Group I- Saline (negative control), Group II- 2% Chlorhexidine gel(CHX), Group III- honey, Group IV- Aloe vera gel, Group V- 20% Curcuma longa gel, Group VI- Propolis gel and Group VII -Calcium hydroxide (CH). At the end of 1, 3 and 5 days, the antimicrobial efficacy of medicaments against E.faecalis was assessed at the depths of 200µm and 400µm. RESULTS: 2% Chlorhexidine gel was most effective followed by Propolis and Curcuma longa. CONCLUSION: 2% Chlorhexidine gel gave the best results. Among the herbal extracts Propolis and Curcuma longa hold a promising future but to implement their use as sole intracanal medicaments clinically, further in vivo and long term studies are warranted.
Authors: Xavier Roig-Soriano; Eliana B Souto; Firas Elmsmari; Maria Luisa Garcia; Marta Espina; Fernando Duran-Sindreu; Elena Sánchez-López; Jose Antonio González Sánchez Journal: Pharmaceutics Date: 2022-07-21 Impact factor: 6.525