| Literature DB >> 29228306 |
Adama Zida1,2,3, Soulama Issiaka4, Bamba Sanata3, Serme S Samuel4,5, Sangare Ibrahim3,6, Sawadogo Marcel1,2, Guiguemde Thierry2,7, Traore Lady Kady2, Guiguemde T Robert2,3.
Abstract
The present investigation aimed to assess the prevalence of genotypes of C. albicans in Ouagadougou and to analyze the relationship between the genetic diversity and antifungal susceptibility. Ninety-six clinical strains are included. They were diagnosed as C. albicans using germ tube test, chlamydospore formation, and Api-Candida test. Genotyping was performed using PCR targeting 25S rDNA. Antifungal susceptibilities were tested based on the disk diffusion method. The genotypes A (85.4%) was predominant followed by genotypes B (10.4%) and C (4.2%). The highest resistance rate with genotype A was obtained with fluconazole (74.4%). A resistance to amphotericin B was observed with genotypes A (29.3%) and B (30%).Entities:
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Year: 2018 PMID： 29228306 DOI： 10.1093/mmy/myx127
Source DB: PubMed Journal: Med Mycol ISSN： 1369-3786 Impact factor: 4.076