Literature DB >> 29228235

The potential role of external venous supports in coronary artery bypass graft surgery.

Jamie A Mawhinney1, Craig A Mounsey1, David P Taggart2.   

Abstract

Despite the apparent superiority of arterial conduits for coronary artery bypass grafting (CABG), the long saphenous vein remains the most commonly used graft. The high failure rate of long saphenous vein grafts (SVGs) over time is therefore an important limiting factor for the long-term outcomes of CABG. Various methods to improve SVG patency have been proposed, although few have had a significant impact on clinical practice. External SVG supports have been a focus of research over the past 50 years, with their use intended to minimize well-documented pathophysiological changes that occur in the SVG following implantation into the coronary circulation. These devices have been trialled extensively in animal models to assess their impact on both the morphology and the function of vascular conduits. Recently, a number of studies have been conducted in patients, leading to a substantial development in their design and the accumulation of a large body of evidence attesting to their potential benefit in CABG. In this review, we briefly discuss the proposed mechanism of action of external SVG supports and then evaluate the results from animal studies and more recent research assessing their use in CABG patients. Finally, we conclude that newer models of external stents have the potential to improve long-term outcomes in SVG.

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Year:  2018        PMID: 29228235     DOI: 10.1093/ejcts/ezx432

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  4 in total

1.  Fluoroscopy Guided Minimally Invasive Swine Model of Myocardial Infarction by Left Coronary Artery Occlusion for Regenerative Cardiology.

Authors:  Finosh G Thankam; Mohamed Radwan; Angelo Keklikian; Manreet Atwal; Taj Rai; Devendra K Agrawal
Journal:  Cardiol Cardiovasc Med       Date:  2022-08-24

Review 2.  Why Use the Radial Artery? The Saphenous Vein is the Second Graft of Choice for CABG in Brazil.

Authors:  Andrzej Loesch; Bruno Botelho Pinheiro; Michael Richard Dashwood
Journal:  Braz J Cardiovasc Surg       Date:  2019-08-27

Review 3.  Twenty-Five Years of No-Touch Saphenous Vein Harvesting for Coronary Artery Bypass Grafting: Structural Observations and Impact on Graft Performance.

Authors:  Ninos Samano; Domingos Souza; Bruno Botelho Pinheiro; Tomislav Kopjar; Michael Dashwood
Journal:  Braz J Cardiovasc Surg       Date:  2020-02-01

4.  Effects of the different-sized external stents on vein graft intimal hyperplasia and inflammation.

Authors:  Qi Yang; Dong Lei; Shixing Huang; Yi Yang; Yang Yang; Xiaofeng Ye; Zhengwei You; Qiang Zhao
Journal:  Ann Transl Med       Date:  2020-02
  4 in total

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