| Literature DB >> 29228115 |
Serafín Pérez-Cerezales1, Priscila Ramos-Ibeas2, Omar Salvador Acuña3, Manuel Avilés4,5, Pilar Coy5,6, Dimitrios Rizos1, Alfonso Gutiérrez-Adán1.
Abstract
The mammalian oviduct is the place where life begins as it is the site of fertilization and preimplantation embryo development. Recent research has highlighted the important role played by the oviduct both in sperm selection for natural fertilization and in the genetic and epigenetic reprogramming of preimplantation embryo development. This review examines oviduct fluid composition with a special emphasis on exosomes and the role played by the oviduct in sperm selection, early embryo development, and in reshaping the epigenetic landscape of the embryo. In addition, the implications of data obtained for improving assisted reproductive technologies are discussed.Entities:
Mesh:
Year: 2018 PMID: 29228115 DOI: 10.1093/biolre/iox173
Source DB: PubMed Journal: Biol Reprod ISSN: 0006-3363 Impact factor: 4.285