Literature DB >> 29227986

Bcl-2 on the brink of breakthroughs in cancer treatment.

John C Reed1,2.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 29227986      PMCID： PMC5729542          DOI： 10.1038/cdd.2017.188

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN： 1350-9047            Impact factor:   15.828


× No keyword cloud information.
  17 in total

1.  The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction.

Authors:  John C Byrd; Shinichi Kitada; Ian W Flinn; Jennifer L Aron; Michael Pearson; David Lucas; John C Reed
Journal:  Blood       Date:  2002-02-01       Impact factor: 22.113

Review 2.  Twenty years on: the impact of fragments on drug discovery.

Authors:  Daniel A Erlanson; Stephen W Fesik; Roderick E Hubbard; Wolfgang Jahnke; Harren Jhoti
Journal:  Nat Rev Drug Discov       Date:  2016-07-15       Impact factor: 84.694

3.  Cancer. Priming cancer cells for death.

Authors:  John C Reed
Journal:  Science       Date:  2011-11-25       Impact factor: 47.728

4.  ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.

Authors:  Andrew J Souers; Joel D Leverson; Erwin R Boghaert; Scott L Ackler; Nathaniel D Catron; Jun Chen; Brian D Dayton; Hong Ding; Sari H Enschede; Wayne J Fairbrother; David C S Huang; Sarah G Hymowitz; Sha Jin; Seong Lin Khaw; Peter J Kovar; Lloyd T Lam; Jackie Lee; Heather L Maecker; Kennan C Marsh; Kylie D Mason; Michael J Mitten; Paul M Nimmer; Anatol Oleksijew; Chang H Park; Cheol-Min Park; Darren C Phillips; Andrew W Roberts; Deepak Sampath; John F Seymour; Morey L Smith; Gerard M Sullivan; Stephen K Tahir; Chris Tse; Michael D Wendt; Yu Xiao; John C Xue; Haichao Zhang; Rod A Humerickhouse; Saul H Rosenberg; Steven W Elmore
Journal:  Nat Med       Date:  2013-01-06       Impact factor: 53.440

Review 5.  Therapeutics targeting Bcl-2 in hematological malignancies.

Authors:  Astrid Ruefli-Brasse; John C Reed
Journal:  Biochem J       Date:  2017-10-23       Impact factor: 3.857

Review 6.  From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors.

Authors:  Avi Ashkenazi; Wayne J Fairbrother; Joel D Leverson; Andrew J Souers
Journal:  Nat Rev Drug Discov       Date:  2017-02-17       Impact factor: 84.694

7.  bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs.

Authors:  T Miyashita; J C Reed
Journal:  Cancer Res       Date:  1992-10-01       Impact factor: 12.701

Review 8.  BCL2 and miR-15/16: from gene discovery to treatment.

Authors:  Yuri Pekarsky; Veronica Balatti; Carlo M Croce
Journal:  Cell Death Differ       Date:  2017-10-06       Impact factor: 15.828

9.  Expression of Bfl-1 in normal and tumor tissues: Bfl-1 overexpression in cancer is attributable to its preferential expression in infiltrating inflammatory cells.

Authors:  H Jung-Ha; D Kim; S B Lee; S I Hong; S Y Park; J Huh; C W Kim; S S Kim; Y Lee; S S Choi; H S Shin
Journal:  Hum Pathol       Date:  1998-07       Impact factor: 3.466

Review 10.  Bcl-2-regulated cell death signalling in the prevention of autoimmunity.

Authors:  D Tischner; C Woess; E Ottina; A Villunger
Journal:  Cell Death Dis       Date:  2010-06-03       Impact factor: 8.469
View more
  11 in total

Review 1.  Targeted Therapy in Chronic Lymphocytic Leukemia.

Authors:  Thomas J Kipps; Michael Y Choi
Journal:  Cancer J       Date:  2019 Nov/Dec       Impact factor: 3.360

Review 2.  Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins.

Authors:  Rumani Singh; Anthony Letai; Kristopher Sarosiek
Journal:  Nat Rev Mol Cell Biol       Date:  2019-03       Impact factor: 94.444

Review 3.  BAG family proteins contributes to autophagy-mediated multidrug resistance of tumor.

Authors:  Jufang Guo; Xuelian Du; Chaolin Li
Journal:  Clin Transl Oncol       Date:  2022-03-12       Impact factor: 3.340

4.  miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins.

Authors:  Yanqin Sun; Bingshuang Hu; Yanhong Wang; Zhen Li; Jingfang Wu; Yunchu Yang; Yue Wei; Xiaofeng Peng; Hongling Chen; Rongqi Chen; Pingyan Jiang; Sixian Fang; Zhiwu Yu; Linlang Guo
Journal:  Cancer Manag Res       Date:  2018-10-18       Impact factor: 3.989

5.  The relationship between the structural characteristics of lactobacilli-EPS and its ability to induce apoptosis in colon cancer cells in vitro.

Authors:  Ummugulsum Tukenmez; Busra Aktas; Belma Aslim; Serkan Yavuz
Journal:  Sci Rep       Date:  2019-06-04       Impact factor: 4.379

6.  Histone methyltransferase WHSC1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic BCL2.

Authors:  Yu Wang; Liming Zhu; Mei Guo; Gang Sun; Kun Zhou; Wenjing Pang; Dachun Cao; Xin Tang; Xiangjun Meng
Journal:  Cell Death Discov       Date:  2021-01-19

Review 7.  Mitochondria as a therapeutic target for common pathologies.

Authors:  Michael P Murphy; Richard C Hartley
Journal:  Nat Rev Drug Discov       Date:  2018-11-05       Impact factor: 84.694

8.  Synergistic anti-proliferative effects of combination of ABT-263 and MCL-1 selective inhibitor A-1210477 on cervical cancer cell lines.

Authors:  Benedict Shi Xiang Lian; Angeline En Hui Yek; Hemalata Shuvas; Siti Fairus Abdul Rahman; Kalaivani Muniandy; Nethia Mohana-Kumaran
Journal:  BMC Res Notes       Date:  2018-03-27

9.  The Deubiquitinating Enzyme Inhibitor PR-619 Enhances the Cytotoxicity of Cisplatin via the Suppression of Anti-Apoptotic Bcl-2 Protein: In Vitro and In Vivo Study.

Authors:  Kuan-Lin Kuo; Shing-Hwa Liu; Wei-Chou Lin; Po-Ming Chow; Yu-Wei Chang; Shao-Ping Yang; Chung-Sheng Shi; Chen-Hsun Hsu; Shih-Ming Liao; Hong-Chiang Chang; Kuo-How Huang
Journal:  Cells       Date:  2019-10-17       Impact factor: 6.600

10.  Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level.

Authors:  Simon Mathis Kønig; Vendela Rissler; Thilde Terkelsen; Matteo Lambrughi; Elena Papaleo
Journal:  PLoS Comput Biol       Date:  2019-12-11       Impact factor: 4.475
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.