Jérôme Lamy1, Gilles Soulat2, Morgane Evin3, Adrian Huber4, Alain de Cesare4, Alain Giron4, Benoit Diebold5, Alban Redheuil6, Elie Mousseaux2, Nadjia Kachenoura3. 1. Sorbonne Universités, UPMC Univ Paris 06, INSERM 1146, CNRS 7371, Laboratoire d'Imagerie Biomédicale, F-75013, Paris, France; ICAN Institute of Cardiometabolism and Nutrition, Paris, France. Electronic address: jerome.jlamy@gmail.com. 2. Centre De Recherche Cardiovasculaire, INSERM, HEGP, Paris, France; Department of Cardiovascular Radiology, European Hospital Georges Pompidou, Paris, France. 3. Sorbonne Universités, UPMC Univ Paris 06, INSERM 1146, CNRS 7371, Laboratoire d'Imagerie Biomédicale, F-75013, Paris, France; ICAN Institute of Cardiometabolism and Nutrition, Paris, France. 4. Sorbonne Universités, UPMC Univ Paris 06, INSERM 1146, CNRS 7371, Laboratoire d'Imagerie Biomédicale, F-75013, Paris, France. 5. Department of Cardiology, European Hospital Georges Pompidou, Paris, France. 6. Sorbonne Universités, UPMC Univ Paris 06, INSERM 1146, CNRS 7371, Laboratoire d'Imagerie Biomédicale, F-75013, Paris, France; ICAN Institute of Cardiometabolism and Nutrition, Paris, France; Department of Cardiovascular and Thoracic Imaging and Interventional Radiology, Institute of Cardiology, Hôpital Pitié-Salpêtrière, Paris, France.
Abstract
BACKGROUND: A feature tracking (FT) was designed to simultaneously extract myocardial strains in main cardiac chambers from cine MRI images. Its inter-observer and scan-rescan reproducibility was assessed and sample sizes required to detect predefined longitudinal changes in strain values were provided. METHOD: FT was applied on left (LV) and right (RV) ventricles as well as left atrium (LA) of 21 individuals (66 ± 10 years) who underwent 2 MRIs 2 weeks apart. Global peaks for radial, circumferential, longitudinal strains, radial motion fraction (Mr), fractional area change (FAC) and tricuspid annular plane excursion (TAPSE) were estimated. Inter-operator and inter-exam reproducibility were evaluated using coefficients of variations (CV) and intra-class correlation coefficients (ICC). RESULTS: Reproducibility of all measurements were good to excellent for inter-operator (LV:CV<6.5%, ICC>0.91; RV:CV<12%, ICC>0.86; LA:CV<14%, ICC>0.85) and inter-study (LV:CV<15%, ICC>0.65; RV:CV<20%, ICC>0.71; LA:CV<20.5%, ICC>0.83) evaluations. Reasonable sample sizes are required to detect a longitudinal difference of 10-15% in strain values (LV:5 to 33 individuals, RV:14 to 62 individuals, LA:4 to 65 individuals). CONCLUSIONS: FT-based functional evaluation of main heart chamber deformation from cine MRI is repeatable and thus suitable for follow-up. Strain measurements may help for the joint clinical evaluation of LV, RV or LA implication in various cardiomyopathies.
BACKGROUND: A feature tracking (FT) was designed to simultaneously extract myocardial strains in main cardiac chambers from cine MRI images. Its inter-observer and scan-rescan reproducibility was assessed and sample sizes required to detect predefined longitudinal changes in strain values were provided. METHOD: FT was applied on left (LV) and right (RV) ventricles as well as left atrium (LA) of 21 individuals (66 ± 10 years) who underwent 2 MRIs 2 weeks apart. Global peaks for radial, circumferential, longitudinal strains, radial motion fraction (Mr), fractional area change (FAC) and tricuspid annular plane excursion (TAPSE) were estimated. Inter-operator and inter-exam reproducibility were evaluated using coefficients of variations (CV) and intra-class correlation coefficients (ICC). RESULTS: Reproducibility of all measurements were good to excellent for inter-operator (LV:CV<6.5%, ICC>0.91; RV:CV<12%, ICC>0.86; LA:CV<14%, ICC>0.85) and inter-study (LV:CV<15%, ICC>0.65; RV:CV<20%, ICC>0.71; LA:CV<20.5%, ICC>0.83) evaluations. Reasonable sample sizes are required to detect a longitudinal difference of 10-15% in strain values (LV:5 to 33 individuals, RV:14 to 62 individuals, LA:4 to 65 individuals). CONCLUSIONS: FT-based functional evaluation of main heart chamber deformation from cine MRI is repeatable and thus suitable for follow-up. Strain measurements may help for the joint clinical evaluation of LV, RV or LA implication in various cardiomyopathies.
Authors: Angela Y Higgins; Amit Arbune; Aaron Soufer; Elio Ragheb; Jennifer M Kwan; Jerome Lamy; Mariana Henry; Jason R Cuomo; Ahmad Charifa; Cesia Gallegos; Sarah Hull; Jessica Shank Coviello; Anna S Bader; Dana C Peters; Steffen Huber; Hamid R Mojibian; Albert J Sinusas; Harriet Kluger; Lauren A Baldassarre Journal: PLoS One Date: 2021-02-19 Impact factor: 3.240
Authors: Sheraz A Nazir; Abhishek M Shetye; Jamal N Khan; Anvesha Singh; Jayanth R Arnold; Iain Squire; Gerry P McCann Journal: Int J Cardiovasc Imaging Date: 2020-03-09 Impact factor: 2.357
Authors: Ricardo A Gonzales; Felicia Seemann; Jérôme Lamy; Per M Arvidsson; Einar Heiberg; Victor Murray; Dana C Peters Journal: BMC Med Imaging Date: 2021-06-19 Impact factor: 1.930