Literature DB >> 29225684

Colon cancer presenting as pseudo-obstruction during pregnancy - A case report.

Reeva Makhijani1, Vicky H Bhagat2, Mariam Fayek2.   

Abstract

The incidence of colorectal cancer in pregnancy is between 0.002 and 0.008%. Diagnosis is often delayed as symptoms of colorectal cancer can mimic as common complaints of pregnancy. We present the case of a 29-year-old with a history of chronic constipation who presented in the second trimester with abdominal pain, inability to tolerate anything orally and no bowel movement in more than three weeks. Non-contrast MRI at presentation failed to show an obstructing mass. Patient was treated conservatively for presumed pseudo-obstruction secondary to worsening constipation from chronic ondansetron use and pregnancy. After four days without clinical improvement, she had a colonoscopy that revealed a completely obstructing sigmoid mass, which biopsies confirmed was a primary colorectal adenocarcinoma. The patient underwent a total abdominal colectomy. She was referred to medical oncology and began adjuvant chemotherapy consisting of 5-fluorouracil, leucovorin and oxaloplatin four weeks post-operatively.

Entities:  

Keywords:  Oncology; gastroenterology; general medicine

Year:  2017        PMID: 29225684      PMCID: PMC5714106          DOI: 10.1177/1753495X17704611

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  14 in total

1.  How does colorectal cancer present? Symptoms, duration, and clues to location.

Authors:  S R Majumdar; R H Fletcher; A T Evans
Journal:  Am J Gastroenterol       Date:  1999-10       Impact factor: 10.864

2.  ACOG Committee Opinion. Number 299, September 2004 (replaces No. 158, September 1995). Guidelines for diagnostic imaging during pregnancy.

Authors: 
Journal:  Obstet Gynecol       Date:  2004-09       Impact factor: 7.661

Review 3.  Symptoms and signs in patients with colorectal cancer.

Authors:  S K P John; S George; J N Primrose; J B J Fozard
Journal:  Colorectal Dis       Date:  2011-01       Impact factor: 3.788

4.  Priorities and uncertainties of administering chemotherapy in a pregnant woman with newly diagnosed colorectal cancer.

Authors:  Abraham S Kanate; Miklos L Auber; Gerald M Higa
Journal:  J Oncol Pharm Pract       Date:  2008-08-27       Impact factor: 1.809

Review 5.  Cancer and pregnancy: a comprehensive review.

Authors:  E Voulgaris; G Pentheroudakis; N Pavlidis
Journal:  Surg Oncol       Date:  2011-07-05       Impact factor: 3.279

Review 6.  Successful twin pregnancy outcome after in utero exposure to FOLFOX for metastatic colon cancer: a case report and review of the literature.

Authors:  Johanne Bakker Jeppesen; Kell Østerlind
Journal:  Clin Colorectal Cancer       Date:  2011-07-30       Impact factor: 4.481

Review 7.  Association between constipation and colorectal cancer: systematic review and meta-analysis of observational studies.

Authors:  Andrew M Power; Nicholas J Talley; Alexander C Ford
Journal:  Am J Gastroenterol       Date:  2013-03-12       Impact factor: 10.864

8.  Administration of oxaliplatin to a pregnant woman with rectal cancer.

Authors:  Michael Gensheimer; Catherine A Jones; Cornelia R Graves; Nipun B Merchant; A Craig Lockhart
Journal:  Cancer Chemother Pharmacol       Date:  2008-03-21       Impact factor: 3.333

9.  Pregnancy-associated colon and rectal cancer: perinatal and cancer outcomes.

Authors:  Mary T Dahling; Guibo Xing; Rosemary Cress; Beate Danielsen; Lloyd H Smith
Journal:  J Matern Fetal Neonatal Med       Date:  2009-03

10.  Perinatal outcomes of a pregnancy complicated by cancer, including neonatal follow-up after in utero exposure to chemotherapy: results of an international registry.

Authors:  Elyce Cardonick; Aniqa Usmani; Sadia Ghaffar
Journal:  Am J Clin Oncol       Date:  2010-06       Impact factor: 2.339

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