Literature DB >> 29225530

Two Targets Are Better Than One: A New Strategy to Increase the Specificity of Anti-Epileptic Drugs.

Matthew C Weston.   

Abstract

Entities:  

Year:  2017        PMID： 29225530      PMCID： PMC5716119          DOI： 10.5698/1535-7597.17.4.235

Source DB:  PubMed          Journal:  Epilepsy Curr        ISSN： 1535-7511            Impact factor:   7.500


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  7 in total

1.  Perampanel, an antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, for the treatment of epilepsy: studies in human epileptic brain and nonepileptic brain and in rodent models.

Authors:  R Zwart; E Sher; X Ping; X Jin; J R Sims; A S Chappell; S D Gleason; P J Hahn; K Gardinier; D L Gernert; J Hobbs; J L Smith; S N Valli; J M Witkin
Journal:  J Pharmacol Exp Ther       Date:  2014-07-15       Impact factor: 4.030

2.  Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.

Authors:  Akihiko S Kato; Kevin D Burris; Kevin M Gardinier; Douglas L Gernert; Warren J Porter; Jon Reel; Chunjin Ding; Yuan Tu; Douglas A Schober; Matthew R Lee; Beverly A Heinz; Thomas E Fitch; Scott D Gleason; John T Catlow; Hong Yu; Stephen M Fitzjohn; Francesca Pasqui; He Wang; Yuewei Qian; Emanuele Sher; Ruud Zwart; Keith A Wafford; Kurt Rasmussen; Paul L Ornstein; John T R Isaac; Eric S Nisenbaum; David S Bredt; Jeffrey M Witkin
Journal:  Nat Med       Date:  2016-11-07       Impact factor: 53.440

3.  Stargazin is an AMPA receptor auxiliary subunit.

Authors:  Wim Vandenberghe; Roger A Nicoll; David S Bredt
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-03       Impact factor: 11.205

4.  Deconstructing behavioral neuropharmacology with cellular specificity.

Authors:  Brenda C Shields; Elizabeth Kahuno; Charles Kim; Pierre F Apostolides; Jennifer Brown; Sarah Lindo; Brett D Mensh; Joshua T Dudman; Luke D Lavis; Michael R Tadross
Journal:  Science       Date:  2017-04-07       Impact factor: 47.728

Review 5.  The expanding social network of ionotropic glutamate receptors: TARPs and other transmembrane auxiliary subunits.

Authors:  Alexander C Jackson; Roger A Nicoll
Journal:  Neuron       Date:  2011-04-28       Impact factor: 17.173

6.  Long-term safety of perampanel and seizure outcomes in refractory partial-onset seizures and secondarily generalized seizures: results from phase III extension study 307.

Authors:  Gregory L Krauss; Emilio Perucca; Elinor Ben-Menachem; Patrick Kwan; Jerry J Shih; Jean-François Clément; Xuefeng Wang; Makarand Bagul; Michelle Gee; Jin Zhu; David Squillacote
Journal:  Epilepsia       Date:  2014-05-27       Impact factor: 5.864

7.  Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins.

Authors:  Susumu Tomita; Lu Chen; Yoshimi Kawasaki; Ronald S Petralia; Robert J Wenthold; Roger A Nicoll; David S Bredt
Journal:  J Cell Biol       Date:  2003-05-26       Impact factor: 10.539
  7 in total

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