| Literature DB >> 29225277 |
Aysegul Kurt1, Subutay Han Altintas2, Mustafa Volkan Kiziltas3, Serife Evrim Tekkeli3, Eray Metin Guler4, Abdurrahim Kocyigit4, Aslihan Usumez5.
Abstract
The aim of this study was to evaluate the amount of leached residual monomers from self-adhesive resin cements and evaluate their toxicity in-vitro. A total of 60 disk-shaped specimens (5 mm in diameter and 0.5 mm in thickness) were prepared from each cement (RelyX U200, SpeedCEM, G-Cem) (n=20). Specimens were immersed in artificial saliva and the amount of released monomers [urethane dimethacrylate (UDMA) and triethyleneglycol dimethacrylate (TEGDMA)] was identified. Then, the cytotoxicity and genotoxicity effect on cells were evaluated using the defined amounts of released monomers from cements. The highest monomer release was detected in G-Cem (p<0.05). The highest cytotoxicity value was identified from SpeedCEM (p<0.01) and the highest genotoxicity values were calculated from RelyX U200 (p<0.05). Released UDMA and TEGDMA from self-adhesive resin cements induced cytotoxicity and genotoxicity effect on cells.Entities:
Keywords: Cytotoxicity; Genotoxicity; Monomer release; Self-adhesive resin cement
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Year: 2017 PMID： 29225277 DOI： 10.4012/dmj.2016-380
Source DB: PubMed Journal: Dent Mater J ISSN： 0287-4547 Impact factor: 2.102