Semiha Terlemez Tokgöz1, Dilek Yılmaz2, Yavuz Tokgöz3, Bülent Çelik4, Yasin Bulut5. 1. 1Pediatric Cardiology Department, Medicine Faculty,Adnan Menderes University,Aydın,Turkey. 2. 2Department of Pediatric Nephrology,Adnan Menderes University,Aydın,Turkey. 3. 3Department of Pediatric,Adnan Menderes University,Aydın,Turkey. 4. 4Faculty Statistics,Gazi University Chemistry,Ankara,Turkey. 5. 5Department of Pediatric,Adnan Menderes University,Aydın,Turkey.
Abstract
BACKGROUND: The aim of this study was to determine and compare cardiovascular risks by assessing arterial stiffness in children with essential hypertension and white coat hypertension. METHODS: Paediatric patients followed up with essential hypertension and white coat hypertension diagnoses and with no established end organ damage were involved in the study. Arterial stiffness in children included in the study was evaluated and compared by using the oscillometric device (Mobil-O-Graph) method. RESULTS: A total of 62 essential hypertension (34 male, 28 female), 38 white coat hypertension (21 male, 17 female), and 60 healthy controls (33 male, 27 female) were assessed in the present study. Pulse wave velocity of the essential hypertension, white coat hypertension, and control group was, respectively, as follows: 5.3±0.6 (m/s), 5.1±0.4 (m/s), 4.3±0.4 (m/s) (p<0.001); augmentation index outcomes were, respectively, determined as follows: 21.3±6.5, 19.3±6.4, 16.0±0.3 (p<0.001). Pulse wave velocity and augmentation index values of children with essential hypertension and white coat hypertension were found to be higher compared with the control group. This level was identified as correlated with the duration of hypertension in both patient groups (p<0.01). CONCLUSION: Arterial stiffness in children with essential hypertension and white coat hypertension was impaired compared with healthy children. This finding has made us think that white coat hypertension is not an innocent clinical situation. This information should be taken into consideration in the follow-up and treatment approaches of the patients.
BACKGROUND: The aim of this study was to determine and compare cardiovascular risks by assessing arterial stiffness in children with essential hypertension and white coat hypertension. METHODS: Paediatric patients followed up with essential hypertension and white coat hypertension diagnoses and with no established end organ damage were involved in the study. Arterial stiffness in children included in the study was evaluated and compared by using the oscillometric device (Mobil-O-Graph) method. RESULTS: A total of 62 essential hypertension (34 male, 28 female), 38 white coat hypertension (21 male, 17 female), and 60 healthy controls (33 male, 27 female) were assessed in the present study. Pulse wave velocity of the essential hypertension, white coat hypertension, and control group was, respectively, as follows: 5.3±0.6 (m/s), 5.1±0.4 (m/s), 4.3±0.4 (m/s) (p<0.001); augmentation index outcomes were, respectively, determined as follows: 21.3±6.5, 19.3±6.4, 16.0±0.3 (p<0.001). Pulse wave velocity and augmentation index values of children with essential hypertension and white coat hypertension were found to be higher compared with the control group. This level was identified as correlated with the duration of hypertension in both patient groups (p<0.01). CONCLUSION: Arterial stiffness in children with essential hypertension and white coat hypertension was impaired compared with healthy children. This finding has made us think that white coat hypertension is not an innocent clinical situation. This information should be taken into consideration in the follow-up and treatment approaches of the patients.
Entities:
Keywords:
Essential hypertension; arterial stiffness; white coat hypertension
Authors: Jessica E Haley; Shalayna A Woodly; Stephen R Daniels; Bonita Falkner; Michael A Ferguson; Joseph T Flynn; Coral D Hanevold; Stephen R Hooper; Julie R Ingelfinger; Philip R Khoury; Marc B Lande; Lisa J Martin; Kevin E Meyers; Mark Mitsnefes; Richard C Becker; Bernard A Rosner; Joshua Samuels; Andrew H Tran; Elaine M Urbina Journal: Hypertension Date: 2022-06-28 Impact factor: 9.897