Literature DB >> 29221348

Lung metastases in an atypical type A thymoma variant.

Masaki Hashimoto1, Yoshitane Tsukamoto2, Shohei Matsuo3, Toru Nakamichi1, Nobuyuki Kondo1, Seiki Hasegawa1.   

Abstract

A 35-year-old woman had undergone extensive thymothymectomy for type A thymoma several years ago. However, two small lung nodules were found 4 and 5 years after surgery. After a partial lung resection to remove these nodules, pathology revealed that they were metastases of the type A thymoma. A pathological re-evaluation confirmed that the primary tumor had in fact been an atypical type A thymoma variant, a subset added to the WHO classification in 2015. Pathology should be re-evaluated in all patients diagnosed with type A thymoma before 2015 since they may have the more aggressive atypical type A thymoma variant.

Entities:  

Keywords:  Thymoma; lung metastasis; necrosis

Year:  2017        PMID: 29221348      PMCID: PMC5708503          DOI: 10.21037/jtd.2017.07.109

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN: 2072-1439            Impact factor:   2.895


  5 in total

Review 1.  The 2015 World Health Organization Classification of Tumors of the Thymus: Continuity and Changes.

Authors:  Alexander Marx; John K C Chan; Jean-Michel Coindre; Frank Detterbeck; Nicolas Girard; Nancy L Harris; Elaine S Jaffe; Michael O Kurrer; Edith M Marom; Andre L Moreira; Kiyoshi Mukai; Attilio Orazi; Philipp Ströbel
Journal:  J Thorac Oncol       Date:  2015-10       Impact factor: 15.609

2.  Is there a spectrum of cytologic atypia in type a thymomas analogous to that seen in type B thymomas? A pilot study of 13 cases.

Authors:  Daisuke Nonaka; Juan Rosai
Journal:  Am J Surg Pathol       Date:  2012-06       Impact factor: 6.394

3.  The World Health Organization histologic classification system reflects the oncologic behavior of thymoma: a clinical study of 273 patients.

Authors:  Meinoshin Okumura; Mitsunori Ohta; Hisashi Tateyama; Katsuhiro Nakagawa; Akihide Matsumura; Hajime Maeda; Hiroto Tada; Tadaaki Eimoto; Hikaru Matsuda; Akira Masaoka
Journal:  Cancer       Date:  2002-02-01       Impact factor: 6.860

4.  The role of histology in predicting recurrence of type A thymomas: a clinicopathologic correlation of 23 cases.

Authors:  I Tudor Vladislav; Yesim Gökmen-Polar; Kenneth A Kesler; Patrick J Loehrer; Sunil Badve
Journal:  Mod Pathol       Date:  2013-04-12       Impact factor: 7.842

5.  A case of atypical type A thymoma variant.

Authors:  Masaki Hashimoto; Shigeki Shimizu; Teruhisa Takuwa; Yoshitane Tsukamoto; Tohru Tsujimura; Seiki Hasegawa
Journal:  Surg Case Rep       Date:  2016-10-21
  5 in total
  2 in total

1.  Type A thymoma with simultaneous solitary intrapulmonary metastasis: A case report.

Authors:  Tsutomu Tatematsu; Katsuhiro Okuda; Katsuhiko Endo; Hideo Hattori; Takuya Matsui; Risa Oda; Tadashi Sakane; Keisuke Yokota; Ryoichi Nakanishi
Journal:  Thorac Cancer       Date:  2021-05-07       Impact factor: 3.500

2.  Small-sized type A thymoma with pulmonary metastasis: a case report.

Authors:  Sachi Kawagishi; Tomohiro Maniwa; Hirokazu Watari; Ryuhei Sakata; Akiisa Omura; Ryo Tanaka; Toru Kimura; Keiichiro Honma; Jiro Okami
Journal:  Surg Case Rep       Date:  2022-01-20
  2 in total

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