Literature DB >> 29220648

Encoding Allostery in mTOR Signaling: The Structure of the Rag GTPase/Ragulator Complex.

Jacqueline Cherfils1.   

Abstract

In this issue of Molecular Cell, Su et al. (2017) describe the structure of the Rag/Ragulator complex, a key relay in nutrient sensing by mTOR. The structure sheds new light on how signals are conveyed from the lysosome to mTOR.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 29220648     DOI： 10.1016/j.molcel.2017.11.027

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  3 in total

1.  Architecture of human Rag GTPase heterodimers and their complex with mTORC1.

Authors:  Madhanagopal Anandapadamanaban; Glenn R Masson; Olga Perisic; Alex Berndt; Jonathan Kaufman; Chris M Johnson; Balaji Santhanam; Kacper B Rogala; David M Sabatini; Roger L Williams
Journal:  Science       Date:  2019-10-11       Impact factor: 47.728

2.  Signal integration in the (m)TORC1 growth pathway.

Authors:  Kailash Ramlaul; Christopher H S Aylett
Journal:  Front Biol (Beijing)       Date:  2018-07-25

3.  TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis.

Authors:  Wen Li; Yulan Li; Yetong Guan; Yingxin Du; Mingsheng Zhao; Xiaotong Chen; Faliang Zhu; Chun Guo; Yufeng Jia; Yuan Li; Xiaoyu Wang; Xiaoyan Wang; Yongyu Shi; Qun Wang; Yan Li; Lining Zhang
Journal:  Autophagy       Date:  2020-05-28       Impact factor: 16.016
  3 in total

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