Literature DB >> 29219146

New traffic light on Th17 Avenue.

Hao Xu1, Dan R Littman1,2.   

Abstract

Activation of STAT3-coupled receptors along with TGF-β signaling are fundamental for Th17 cell differentiation both in vivo and in vitro. A recent paper shows that TGF-β signaling relieves SKI-mediated transcriptional repression of Rorc, the key regulator of the Th17 program.

Entities:  

Mesh：

Substances：

Year:  2017        PMID： 29219146      PMCID： PMC5799815          DOI： 10.1038/cr.2017.156

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  10 in total

1.  T-bet and eomesodermin play critical roles in directing T cell differentiation to Th1 versus Th17.

Authors:  Yu Yang; Jiangnan Xu; Yanyan Niu; Jonathan S Bromberg; Yaozhong Ding
Journal:  J Immunol       Date:  2008-12-15       Impact factor: 5.422

Review 2.  IL-17 and Th17 Cells.

Authors:  Thomas Korn; Estelle Bettelli; Mohamed Oukka; Vijay K Kuchroo
Journal:  Annu Rev Immunol       Date:  2009       Impact factor: 28.527

Review 3.  The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing.

Authors:  Sarah L Gaffen; Renu Jain; Abhishek V Garg; Daniel J Cua
Journal:  Nat Rev Immunol       Date:  2014-09       Impact factor: 53.106

Review 4.  Ski/Sno and TGF-beta signaling.

Authors:  X Liu; Y Sun; R A Weinberg; H F Lodish
Journal:  Cytokine Growth Factor Rev       Date:  2001-03       Impact factor: 7.638

5.  The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

Authors:  Ivaylo I Ivanov; Brent S McKenzie; Liang Zhou; Carlos E Tadokoro; Alice Lepelley; Juan J Lafaille; Daniel J Cua; Dan R Littman
Journal:  Cell       Date:  2006-09-22       Impact factor: 41.582

6.  A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling.

Authors:  Ai-Di Gu; Song Zhang; Yunqi Wang; Hui Xiong; Thomas A Curtis; Yisong Y Wan
Journal:  Immunity       Date:  2014-12-25       Impact factor: 31.745

7.  TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells.

Authors:  Marc Veldhoen; Richard J Hocking; Christopher J Atkins; Richard M Locksley; Brigitta Stockinger
Journal:  Immunity       Date:  2006-02       Impact factor: 31.745

8.  Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling.

Authors:  Kamran Ghoreschi; Arian Laurence; Xiang-Ping Yang; Cristina M Tato; Mandy J McGeachy; Joanne E Konkel; Haydeé L Ramos; Lai Wei; Todd S Davidson; Nicolas Bouladoux; John R Grainger; Qian Chen; Yuka Kanno; Wendy T Watford; Hong-Wei Sun; Gérard Eberl; Ethan M Shevach; Yasmine Belkaid; Daniel J Cua; Wanjun Chen; John J O'Shea
Journal:  Nature       Date:  2010-10-21       Impact factor: 49.962

9.  Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation.

Authors:  Jyoti Das; Guangwen Ren; Liying Zhang; Arthur I Roberts; Xin Zhao; Alfred L M Bothwell; Luc Van Kaer; Yufang Shi; Gobardhan Das
Journal:  J Exp Med       Date:  2009-09-28       Impact factor: 14.307

10.  Reversing SKI-SMAD4-mediated suppression is essential for TH17 cell differentiation.

Authors:  Song Zhang; Motoki Takaku; Liyun Zou; Ai-di Gu; Wei-Chun Chou; Ge Zhang; Bing Wu; Qing Kong; Seddon Y Thomas; Jonathan S Serody; Xian Chen; Xiaojiang Xu; Paul A Wade; Donald N Cook; Jenny P Y Ting; Yisong Y Wan
Journal:  Nature       Date:  2017-10-25       Impact factor: 49.962
  10 in total
  3 in total

1.  Norcantharidin ameliorates the development of murine lupus via inhibiting the generation of IL-17 producing cells.

Authors:  Li-Jun Du; Yu-Xiang Feng; Zhi-Xing He; Lin Huang; Qiao Wang; Cheng-Ping Wen; Yun Zhang
Journal:  Acta Pharmacol Sin       Date:  2021-09-22       Impact factor: 7.169

2.  The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice.

Authors:  Alyssa Chaffey; Glenn Hamonic; Dylan Chand; George K Mutwiri; Heather L Wilson
Journal:  Vaccines (Basel)       Date:  2021-05-14

3.  Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice.

Authors:  Renato Fraga Righetti; Tabata Maruyama Dos Santos; Leandro do Nascimento Camargo; Luciana Ritha Cássia Rolim Barbosa Aristóteles; Silvia Fukuzaki; Flávia Castro Ribas de Souza; Fernanda Paula Roncon Santana; Marcus Vinicius Rodrigues de Agrela; Maysa Mariana Cruz; Maria Isabel Cardoso Alonso-Vale; Isabella Santos Genaro; Beatriz Mangueira Saraiva-Romanholo; Edna Aparecida Leick; Milton de Arruda Martins; Carla Máximo Prado; Iolanda de Fátima Lopes Calvo Tibério
Journal:  Front Pharmacol       Date:  2018-10-04       Impact factor: 5.810
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.