Literature DB >> 29218899

PRECISION MEDICINE: FROM DIPLOTYPES TO DISPARITIES TOWARDS IMPROVED HEALTH AND THERAPIES.

Dana C Crawford1, Alexander A Morgan, Joshua C Denny, Bruce J Aronow, Steven E Brenner.   

Abstract

Precision medicine research efforts both in basic science discovery and clinical implementation are well underway and promise to provide individualized preventions and treatments, improving overall health care delivery. To achieve these goals, advances in data capture and analysis are needed spanning different types of 'omic and clinical data. The efforts to enhance precise treatments for all may accentuate healthcare disparities unless specific challenges are identified and addressed. This session of the 2018 Pacific Symposium on Biocomputing presents the latest developments in this transdisciplinary research space of genomics, medicine, and population health.

Entities:  

Year:  2018        PMID： 29218899      PMCID： PMC6182117     

Source DB:  PubMed          Journal:  Pac Symp Biocomput        ISSN： 2335-6928


  66 in total

Review 1.  Personalized medicine: been there, done that, always needs work!

Authors:  John F Murray
Journal:  Am J Respir Crit Care Med       Date:  2012-06-15       Impact factor: 21.405

Review 2.  The social determinants of health: coming of age.

Authors:  Paula Braveman; Susan Egerter; David R Williams
Journal:  Annu Rev Public Health       Date:  2011       Impact factor: 21.981

Review 3.  Diagnostic clinical genome and exome sequencing.

Authors:  Leslie G Biesecker; Robert C Green
Journal:  N Engl J Med       Date:  2014-06-19       Impact factor: 91.245

4.  A pharmacogenetic versus a clinical algorithm for warfarin dosing.

Authors:  Stephen E Kimmel; Benjamin French; Scott E Kasner; Julie A Johnson; Jeffrey L Anderson; Brian F Gage; Yves D Rosenberg; Charles S Eby; Rosemary A Madigan; Robert B McBane; Sherif Z Abdel-Rahman; Scott M Stevens; Steven Yale; Emile R Mohler; Margaret C Fang; Vinay Shah; Richard B Horenstein; Nita A Limdi; James A S Muldowney; Jaspal Gujral; Patrice Delafontaine; Robert J Desnick; Thomas L Ortel; Henny H Billett; Robert C Pendleton; Nancy L Geller; Jonathan L Halperin; Samuel Z Goldhaber; Michael D Caldwell; Robert M Califf; Jonas H Ellenberg
Journal:  N Engl J Med       Date:  2013-11-19       Impact factor: 91.245

5.  Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Authors:  Aravind Subramanian; Pablo Tamayo; Vamsi K Mootha; Sayan Mukherjee; Benjamin L Ebert; Michael A Gillette; Amanda Paulovich; Scott L Pomeroy; Todd R Golub; Eric S Lander; Jill P Mesirov
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-30       Impact factor: 11.205

6.  Emergence of pathway-level composite biomarkers from converging gene set signals of heterogeneous transcriptomic responses.

Authors:  Samir Rachid Zaim; Qike Li; A Grant Schissler; Yves A Lussier
Journal:  Pac Symp Biocomput       Date:  2018

7.  What is translational genomics? An expanded research agenda for improving individual and population health.

Authors:  Sheri D Schully; Muin J Khoury
Journal:  Appl Transl Genom       Date:  2014-12

8.  Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals.

Authors:  Alexis Battle; Sara Mostafavi; Xiaowei Zhu; James B Potash; Myrna M Weissman; Courtney McCormick; Christian D Haudenschild; Kenneth B Beckman; Jianxin Shi; Rui Mei; Alexander E Urban; Stephen B Montgomery; Douglas F Levinson; Daphne Koller
Journal:  Genome Res       Date:  2013-10-03       Impact factor: 9.043

9.  Expansion of the Gene Ontology knowledgebase and resources.

Authors: 
Journal:  Nucleic Acids Res       Date:  2016-11-29       Impact factor: 16.971

10.  Computing power and sample size for case-control association studies with copy number polymorphism: application of mixture-based likelihood ratio test.

Authors:  Wonkuk Kim; Derek Gordon; Jonathan Sebat; Kenny Q Ye; Stephen J Finch
Journal:  PLoS One       Date:  2008-10-22       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.