| Literature DB >> 29217720 |
Merryn Gott1, Joanna Broad2, Xian Zhang2, Lene Jarlbaek3, David Clark4.
Abstract
OBJECTIVES: (1) To establish the likelihood of dying within 12 months for a cohort of hospital inpatients in New Zealand (NZ) on a fixed census date; (2) to identify associations between likelihood of death and key sociodemographic, diagnostic and service-related factors and (3) to compare results with, and extend findings of, a Scottish study undertaken for the same time period and census date. National databases of hospitalisations and death registrations were used, linked by unique health identifier. PARTICIPANTS: 6074 patients stayed overnight in NZ hospitals on the census date (10 April 2013), 40.8% of whom were aged ≥65 years; 54.4% were women; 69.1% of patients were NZ European; 15.3% were Maori; 7.6% were Pacific; 6.1% were Asian and 1.9% were 'other'.Entities:
Keywords: death; end of life; ethnicity; hospital; mortality; palliative care
Mesh:
Year: 2017 PMID: 29217720 PMCID: PMC5728296 DOI: 10.1136/bmjopen-2017-016880
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Demographics, hospitalisations and mortality of cohort
| In hospital on | Died within | Died within | Died within | Died within | Died within | Died within | ||||||||
| n=6074 | n=98 | n=276 | n=488 | n=665 | n=768 | n=878 | ||||||||
| n | Col % | n | Row % | n | Row % | n | Row % | n | Row % | n | Row % | n | Row % | |
| All | 6074 | 100.0 | 98 | 1.6 | 276 | 4.5 | 488 | 8.0 | 665 | 10.9 | 768 | 12.6 | 878 | 14.5 |
| Gender | ||||||||||||||
| Woman | 3302 | 54.4 | 48 | 1.5 | 141 | 4.3 | 249 | 7.5 | 331 | 10.0 | 381 | 11.5 | 432 | 13.1 |
| Man | 2772 | 45.6 | 50 | 1.8 | 135 | 4.9 | 239 | 8.6 | 334 | 12.0 | 387 | 14.0 | 446 | 16.1 |
| Age at discharge (year) | ||||||||||||||
| 0–14 | 949 | 15.6 | 3 | 0.3 | 5 | 0.5 | 9 | 0.9 | 13 | 1.4 | 14 | 1.5 | 17 | 1.8 |
| 15–59 | 2269 | 37.4 | 20 | 0.9 | 47 | 2.1 | 78 | 3.4 | 107 | 4.7 | 127 | 5.6 | 154 | 6.8 |
| 60–64 | 376 | 6.2 | 5 | 1.3 | 18 | 4.8 | 36 | 9.6 | 50 | 13.3 | 53 | 14.1 | 59 | 15.7 |
| 65–69 | 476 | 7.8 | 6 | 1.3 | 15 | 3.2 | 36 | 7.6 | 58 | 12.2 | 74 | 15.5 | 79 | 16.6 |
| 70–74 | 469 | 7.7 | 13 | 2.8 | 32 | 6.8 | 56 | 11.9 | 78 | 16.6 | 89 | 19.0 | 104 | 22.2 |
| 75–79 | 472 | 7.8 | 9 | 1.9 | 34 | 7.2 | 66 | 14.0 | 87 | 18.4 | 99 | 21.0 | 114 | 24.2 |
| 80–84 | 487 | 8.0 | 15 | 3.1 | 56 | 11.5 | 85 | 17.5 | 110 | 22.6 | 129 | 26.5 | 141 | 29.0 |
| ≥85 years | 576 | 9.5 | 27 | 4.7 | 69 | 12.0 | 122 | 21.2 | 162 | 28.1 | 183 | 31.8 | 210 | 36.5 |
| Prioritised ethnicity | ||||||||||||||
| European | 4198 | 69.1 | 74 | 1.8 | 214 | 5.1 | 368 | 8.8 | 505 | 12.0 | 584 | 13.9 | 661 | 15.7 |
| Māori | 931 | 15.3 | 11 | 1.2 | 27 | 2.9 | 56 | 6.0 | 85 | 9.1 | 96 | 10.3 | 118 | 12.7 |
| Pacific | 460 | 7.6 | 8 | 1.7 | 19 | 4.1 | 31 | 6.7 | 40 | 8.7 | 47 | 10.2 | 53 | 11.5 |
| Asian | 369 | 6.1 | 4 | 1.1 | 11 | 3.0 | 21 | 5.7 | 23 | 6.2 | 25 | 6.8 | 27 | 7.3 |
| Other | 116 | 1.9 | 1 | 0.9 | 5 | 4.3 | 12 | 10.3 | 12 | 10.3 | 16 | 13.8 | 19 | 16.4 |
| Specialty of index stay | ||||||||||||||
| Medicine | 2621 | 43.2 | 81 | 3.1 | 220 | 8.4 | 380 | 14.5 | 511 | 19.5 | 581 | 22.2 | 654 | 25.0 |
| Surgery | 2490 | 41.0 | 15 | 0.6 | 53 | 2.1 | 103 | 4.1 | 148 | 5.9 | 181 | 7.3 | 217 | 8.7 |
| Procedure | 963 | 15.9 | 2 | 0.2 | 3 | 0.3 | 5 | 0.5 | 6 | 0.6 | 6 | 0.6 | 7 | 0.7 |
| Admission type of index stay | ||||||||||||||
| Acute admission | 4117 | 67.8 | 89 | 2.2 | 249 | 6.0 | 433 | 10.5 | 582 | 14.1 | 661 | 16.1 | 749 | 18.2 |
| Arranged admission | 1093 | 18.0 | 9 | 0.8 | 25 | 2.3 | 46 | 4.2 | 60 | 5.5 | 74 | 6.8 | 84 | 7.7 |
| Admission from waitlist | 864 | 14.2 | 0 | – | 2 | 0.2 | 9 | 1.0 | 23 | 2.7 | 33 | 3.8 | 45 | 5.2 |
| Any record of cancer (this or prior hospital stay) | ||||||||||||||
| No | 4778 | 78.7 | 62 | 1.3 | 142 | 3.0 | 240 | 5.0 | 330 | 6.9 | 386 | 8.1 | 448 | 9.4 |
| Yes | 1296 | 21.3 | 36 | 2.8 | 134 | 10.3 | 248 | 19.1 | 335 | 25.8 | 382 | 29.5 | 430 | 33.2 |
| Deprivation quintile (NZDep06)† | ||||||||||||||
| Q1 (most deprived) | 1584 | 26.1 | 28 | 1.8 | 76 | 4.8 | 133 | 8.4 | 180 | 11.4 | 207 | 13.1 | 235 | 14.8 |
| Q2 | 1434 | 23.6 | 19 | 1.3 | 68 | 4.7 | 107 | 7.5 | 155 | 10.8 | 181 | 12.6 | 210 | 14.6 |
| Q3 | 1257 | 20.7 | 14 | 1.1 | 46 | 3.7 | 92 | 7.3 | 132 | 10.5 | 157 | 12.5 | 185 | 14.7 |
| Q4 | 945 | 15.6 | 26 | 2.8 | 51 | 5.4 | 91 | 9.6 | 115 | 12.2 | 129 | 13.7 | 141 | 14.9 |
| Q5 (least deprived) | 809 | 13.3 | 10 | 1.2 | 29 | 3.6 | 58 | 7.2 | 75 | 9.3 | 86 | 10.6 | 98 | 12.1 |
Row and Column %s add up to 100.
*Only publicly funded hospitalisations included.
†45 patients have no deprivation information.
NZDep06, New Zealand Deprivation Index 2006 decile.
Diagnoses of index hospitalisation and of prior hospitalisations
| In hospital on | Died within | Died within | Died within | Died within | Died within | Died within | ||||||||
| n=6074 | n=98 | n=276 | n=488 | n=665 | n=768 | n=878 | ||||||||
| n | Col % | n | Row % | n | Row % | n | Row % | n | Row % | n | Row % | n | Row % | |
| All* | 6074 | 100.0 | 98 | 1.6 | 276 | 4.5 | 488 | 8.0 | 665 | 10.9 | 768 | 12.6 | 878 | 14.5 |
| Primary diagnosis of the index stay | ||||||||||||||
| Circulatory (I) | 803 | 13.2 | 21 | 2.6 | 59 | 7.3 | 89 | 11.1 | 125 | 15.6 | 137 | 17.1 | 153 | 19.1 |
| Injury, poisoning and other consequences of external causes (S, T) | 788 | 13.0 | 10 | 1.3 | 22 | 2.8 | 40 | 5.1 | 51 | 6.5 | 61 | 7.7 | 79 | 10.0 |
| Digestive (K) | 600 | 9.9 | 8 | 1.3 | 22 | 3.7 | 37 | 6.2 | 52 | 8.7 | 63 | 10.5 | 72 | 12.0 |
| Cancer (C, D00-D49) | 536 | 8.8 | 17 | 3.2 | 59 | 11.0 | 117 | 21.8 | 151 | 28.2 | 175 | 32.6 | 197 | 36.8 |
| Pregnancy and childbirth (O) | 460 | 7.6 | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – | 0 | – |
| Respiratory (J) | 408 | 6.7 | 18 | 4.4 | 35 | 8.6 | 54 | 13.2 | 83 | 20.3 | 96 | 23.5 | 101 | 24.8 |
| Musculoskeletal (M) | 392 | 6.5 | 2 | 0.5 | 6 | 1.5 | 16 | 4.1 | 21 | 5.4 | 23 | 5.9 | 26 | 6.6 |
| Conditions originating in perinatal period (P) | 339 | 5.6 | 2 | 0.6 | 3 | 0.9 | 5 | 1.5 | 6 | 1.8 | 6 | 1.8 | 7 | 2.1 |
| Other symptoms and signs (R) | 312 | 5.1 | 2 | 0.6 | 14 | 4.5 | 23 | 7.4 | 33 | 10.6 | 38 | 12.2 | 46 | 14.7 |
| Factors influencing health status (Z) | 277 | 4.6 | 0 | – | 2 | 0.7 | 4 | 1.4 | 5 | 1.8 | 8 | 2.9 | 9 | 3.2 |
| Genitourinary (N) | 264 | 4.3 | 5 | 1.9 | 9 | 3.4 | 19 | 7.2 | 27 | 10.2 | 32 | 12.1 | 37 | 14.0 |
| Skin and subcutaneous tissue (L) | 197 | 3.2 | 1 | 0.5 | 7 | 3.6 | 11 | 5.6 | 14 | 7.1 | 18 | 9.1 | 20 | 10.2 |
| Endocrine, nutritional and metabolic diseases (E) | 196 | 3.2 | 2 | 1.0 | 12 | 6.1 | 26 | 13.3 | 37 | 18.9 | 44 | 22.4 | 52 | 26.5 |
| Nervous, eye and ear (G, H) | 177 | 2.9 | 1 | 0.6 | 4 | 2.3 | 12 | 6.8 | 16 | 9.0 | 18 | 10.2 | 20 | 11.3 |
| Infectious and parasitic diseases (A, B) | 170 | 2.8 | 8 | 4.7 | 21 | 12.4 | 25 | 14.7 | 31 | 18.2 | 33 | 19.4 | 39 | 22.9 |
| Congenital malformations (Q) | 74 | 1.2 | 1 | 1.4 | 1 | 1.4 | 3 | 4.1 | 5 | 6.8 | 6 | 8.1 | 6 | 8.1 |
| Blood and immune diseases (D50-D89) | 39 | 0.6 | 0 | – | 0 | – | 3 | 7.7 | 3 | 7.7 | 3 | 7.7 | 5 | 12.8 |
| Mental and behavioural disorders (F) | 42 | 0.7 | 0 | – | 0 | – | 4 | 9.5 | 5 | 11.9 | 7 | 16.7 | 9 | 21.4 |
| Prior hospitalisation history as at census date† | ||||||||||||||
| Circulatory (I) | 2946 | 48.5 | 81 | 2.7 | 220 | 7.5 | 373 | 12.7 | 509 | 17.3 | 589 | 20.0 | 673 | 22.8 |
| Digestive (K) | 2759 | 45.4 | 67 | 2.4 | 193 | 7.0 | 334 | 12.1 | 453 | 16.4 | 520 | 18.8 | 593 | 21.5 |
| Injury, poisoning, external cause (S, T) | 2548 | 41.9 | 42 | 1.6 | 130 | 5.1 | 252 | 9.9 | 348 | 13.7 | 405 | 15.9 | 475 | 18.6 |
| Respiratory (J) | 1896 | 31.2 | 59 | 3.1 | 171 | 9.0 | 292 | 15.4 | 383 | 20.2 | 436 | 23.0 | 497 | 26.2 |
| Cancer | 1296 | 21.3 | 36 | 2.8 | 134 | 10.3 | 248 | 19.1 | 335 | 25.8 | 382 | 29.5 | 430 | 33.2 |
Col % indicates the percentage of all deaths that occur within each diagnosis group. Row % summarises the proportion of those in each diagnosis group who died each time interval.
*Only publicly funded hospitalisations included.
†As defined by ICD-10 primary diagnosis code.
ICD-10, International Classification of Diseases 10th Revision.
Figure 1Deaths within 12 months of census date by primary diagnosis of hospitalisation.
Comparison of three predictive models for death within 12 months
| Model 1 | Model 2 | Model 3 | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Gender (man vs woman) | 1.15 (0.98 to 1.35) | 1.13 (0.96 to 1.33) | 1.09 (0.92 to 1.28) |
| P value | 0.076 | 0.146 | 0.324 |
| Age group (vs 15–59 years) | |||
| 0–14 | 0.32 (0.19 to 0.54) | 0.36 (0.21 to 0.62) | 0.40 (0.23 to 0.69) |
| 60–64 | 2.06 (1.48 to 2.87) | 1.86 (1.31 to 2.64) | 1.70 (1.20 to 2.43) |
| 65–69 | 2.18 (1.61 to 2.94) | 2.19 (1.60 to 2.99) | 1.92 (1.39 to 2.65) |
| 70–74 | 3.07 (2.32 to 4.08) | 2.93 (2.17 to 3.96) | 2.48 (1.82 to 3.38) |
| 75–79 | 3.27 (2.47 to 4.32) | 3.52 (2.62 to 4.73) | 2.90 (2.14 to 3.93) |
| 80–84 | 4.12 (3.15 to 5.38) | 4.03 (3.01 to 5.38) | 3.48 (2.59 to 4.69) |
| 85+years | 5.52 (4.31 to 7.07) | 6.07 (4.63 to 7.96) | 4.89 (3.69 to 6.47) |
| P value | <0.0001 | <0.0001 | <0.0001 |
| Deprivation quintile (vs Q5, least deprived) | |||
| Q1 (most deprived) | 1.54 (1.17 to 2.02) | 1.45 (1.08 to 1.94) | 1.34 (1.00 to 1.81) |
| Q2 | 1.28 (0.97 to 1.69) | 1.23 (0.92 to 1.64) | 1.19 (0.89 to 1.59) |
| Q3 | 1.31 (0.99 to 1.74) | 1.34 (0.99 to 1.80) | 1.30 (0.96 to 1.75) |
| Q4 | 1.24 (0.92 to 1.67) | 1.26 (0.92 to 1.72) | 1.22 (0.89 to 1.67) |
| P value | 0.038 | 0.165 | 0.364 |
| Specialty (vs surgical) | |||
| Medical | 3.16 (2.66 to 3.76) | 2.57 (2.12 to 3.12) | 2.37 (1.94 to 2.89) |
| Procedure | 0.26 (0.12 to 0.57) | 0.31 (0.14 to 0.69) | 0.47 (0.21 to 1.07) |
| P value | <0.0001 | <0.0001 | <0.0001 |
| Ethnicity (vs European/NZ) | |||
| Māori | 1.62 (1.25 to 2.10) | 1.52 (1.17 to 1.98) | |
| Pacific | 1.25 (0.87 to 1.80) | 1.20 (0.83 to 1.74) | |
| Asian | 1.02 (0.65 to 1.60) | 1.02 (0.64 to 1.61) | |
| Other | 1.67 (0.95 to 2.92) | 1.91 (1.08 to 3.38) | |
| P value | 0.0039 | 0.009 | |
| Admission type (vs acute) | |||
| Waitlisted | 0.34 (0.24 to 0.48) | 0.37 (0.26 to 0.52) | |
| Arranged | 0.94 (0.71 to 1.25) | 0.87 (0.65 to 1.15) | |
| P value | <0.0001 | <0.0001 | |
| Hospitalisation history (yes vs no) | |||
| Cancer | 4.20 (3.53 to 4.98) | 3.92 (3.29 to 4.67) | |
| P value | <0.0001 | <0.0001 | |
| Respiratory | 1.82 (1.53 to 2.16) | ||
| P value | <0.0001 | ||
| Digestive | 1.51 (1.26 to 1.80) | ||
| P value | <0.0001 | ||
| Circulatory | 1.34 (1.09, 1.64) | ||
| P value | 0.0048 | ||
| Injury, poisoning, external cause | 1.08 (0.91 to 1.28) | ||
| P value | 0.378 | ||
| Model fit | |||
| C-index | 0.79 | 0.84 | 0.85 |
45 people were omitted from all models because of missing data for deprivation.