| Literature DB >> 2921643 |
A Robertson1, J N Morrison, A M Wood, I Bremner.
Abstract
The effects of iron deficiency and of restriction of food intake on blood and tissue metallothionein-I (MT-I) concentrations in rats were investigated. Compared to ad libitum fed controls, MT-I concentrations in the blood cells of the iron-deficient rats were higher, whereas concentrations in pair-fed control rats were lower. Iron deficiency also increased MT-I concentrations in the bone marrow but concentrations in the liver were unchanged and those in the kidneys were reduced. The MT-I in the blood cells was associated mainly with the lighter cell fractions which were rich in reticulocytes. It is suggested that concentrations of MT-I in blood cells reflect erythropoietic activity.Entities:
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Year: 1989 PMID： 2921643 DOI： 10.1093/jn/119.3.439
Source DB: PubMed Journal: J Nutr ISSN： 0022-3166 Impact factor: 4.798