Literature DB >> 29215622

Novel PRSS1 Mutation p.P17T Validates Pathogenic Relevance of CTRC-Mediated Processing of the Trypsinogen Activation Peptide in Chronic Pancreatitis.

Balázs Csaba Németh1,2, Ákos Szücs3, Péter Hegyi4,5, Miklós Sahin-Tóth1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2017        PMID： 29215622      PMCID： PMC5933932          DOI： 10.1038/ajg.2017.393

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN： 0002-9270            Impact factor:   10.864


× No keyword cloud information.
  5 in total

1.  High Penetrance of the PRSS1 A16V Mutation in a Kindred With SPINK1 N34S and CFTR TG11-5T Co-mutations.

Authors:  Robert A Moran; Noe Quesada-Vazquez; Amitasha Sinha; Enrique de-Madaria; Vikesh K Singh
Journal:  Pancreas       Date:  2016-01       Impact factor: 3.327

2.  Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.

Authors:  András Szabó; Miklós Sahin-Tóth
Journal:  J Biol Chem       Date:  2012-04-26       Impact factor: 5.157

3.  Chymotrypsin C (caldecrin) stimulates autoactivation of human cationic trypsinogen.

Authors:  Zsófia Nemoda; Miklós Sahin-Tóth
Journal:  J Biol Chem       Date:  2006-02-27       Impact factor: 5.157

4.  The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families.

Authors:  Christopher J Grocock; Vinciane Rebours; Myriam N Delhaye; Ake Andrén-Sandberg; Frank Ulrich Weiss; Roger Mountford; Matthew J Harcus; Edyta Niemczyck; Louis J Vitone; Susanna Dodd; Maiken Thyregod Jørgensen; Rudolf W Ammann; Ove Schaffalitzky de Muckadell; Jane V Butler; Phillip Burgess; Bronwyn Kerr; Richard Charnley; Robert Sutton; Michael G Raraty; Jacques Devière; David C Whitcomb; John P Neoptolemos; Philippe Lévy; Markus M Lerch; William Greenhalf
Journal:  Gut       Date:  2009-12-01       Impact factor: 23.059

Review 5.  Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway.

Authors:  Eszter Hegyi; Miklós Sahin-Tóth
Journal:  Dig Dis Sci       Date:  2017-05-23       Impact factor: 3.199
  5 in total
  4 in total

1.  Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice.

Authors:  Andrea Geisz; Zsanett Jancsó; Balázs Csaba Németh; Eszter Hegyi; Miklós Sahin-Tóth
Journal:  JCI Insight       Date:  2019-06-18

2.  Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.

Authors:  Anna Orekhova; Balázs Csaba Németh; Zsanett Jancsó; Andrea Geisz; Dóra Mosztbacher; Alexandra Demcsák; Miklós Sahin-Tóth
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2021-10-13       Impact factor: 4.052

Review 3.  Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.

Authors:  Wen-Bin Zou; David N Cooper; Emmanuelle Masson; Na Pu; Zhuan Liao; Claude Férec; Jian-Min Chen
Journal:  Hum Genet       Date:  2022-01-28       Impact factor: 5.881

Review 4.  Genetics, Cell Biology, and Pathophysiology of Pancreatitis.

Authors:  Julia Mayerle; Matthias Sendler; Eszter Hegyi; Georg Beyer; Markus M Lerch; Miklós Sahin-Tóth
Journal:  Gastroenterology       Date:  2019-01-18       Impact factor: 22.682
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.