| Literature DB >> 29214692 |
Abstract
Freeze frame: The Nobel Prize in Chemistry 2017 was jointly awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson for "developing cryo-electron microscopy (cryo-EM) for the high-resolution structure determination of biomolecules in solution". This Highlight describes how the field of cryo-EM developed from the first transmission electron microscope in 1931 to the sophisticated technique of today.Keywords: cryo-EM; drug discovery; electron microscopy; protein structures; structural biology
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Year: 2017 PMID： 29214692 DOI： 10.1002/anie.201710679
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336