In this issue we are publishing a series of articles that constitute the new
recommendations of the Scientific Department of Cognitive Neurology and Aging of the
Brazilian Academy of Neurology (SDCNA-BAN) for the diagnosis and treatment of
Alzheimer’s disease (AD) in Brazil. In 2005, recommendations were published by this same
scientific department regarding the criteria to be used for the diagnosis of AD in
Brazil, as well as the neuropsychological tests and questionnaires or validated scales
that were more suitable for employment in Brazil, and recommendations regarding the
treatment of AD.[1-3] This year, the Alzheimer’s Association published new
criteria[4] that modify
substantially the previous ones published in 1984,[5] mainly because they include the possibility of preclinical
diagnosis of AD and change the operational concept of dementia. The SDCNA-BAN adapted
their recommendations to these new concepts and criteria as well as updated the items of
neuropsychological evaluation and the recommendations regarding the treatment of
cognitive, psychological and behavioral symptoms in AD.In the article by Frota et al., it is evident that “dementia of AD” is now
the substitute term for what was previously known as AD, as this disease can be
diagnosed before the occurrence of any cognitive decline in its preclinical phase. The
paper makes it clear that the diagnosis of preclinical AD is of interest for research
and not for clinical use. The authors also stressed that the presence of memory decline
is not a sine qua non condition for the diagnosis of dementia in AD or
in other subtypes of dementia.Chaves et al. carried out a systematic review of the literature to recommend
tests, scales and batteries for use in the Brazilian population for the diagnosis of AD,
according to the level of evidence. The authors also concluded that more validation
studies should be performed.Caramelli et al. evaluated, through a systematic assessment of the consensus
reached in other countries and in Brazil, which are the supplementary exams that should
be employed for the clinical diagnosis of AD.Vale et al. carried out a systematic review to recommend the best available
pharmacologic and non-pharmacologic treatments for the cognitive symptoms of the
dementia of AD in Brazil. The recommendations were classified into four leves of
evidence.Vale et al. also evaluated the best pharmacologic and non-pharmacologic
treatments for the psychological and behavioral disturbances in AD in Brazil, through a
systematic review of the literature.Moraes et al. compared the performance of depressive elderly, healthy older
adults and healthy young in a dual-task performance. Significant differences were
observed between young and old individuals.Kochhann et al. evaluated the association of AD caregivers’ burden with
several characteristics of the patients and concluded that neuropsychiatric symptoms
were the main determinants of burden.Ribas et al. compared excessive sleepiness in air traffic controllers and in
control individuals using the Epworth Sleepiness Scale and the Maintenance of
Wakefulness Test. Air traffic controllers exhibit excessive sleepiness.Ordonez et al. compared the subjective well-being of elderly attending a
third age open university for more than one semester with those starting the educational
program. Participants who attended the Third Age Open University for six months or more
had higher degrees of satisfaction and higher rates of psychological adjustment when
compared to those beginning the university program.Ponce et al. evaluated the impact of a psychoeducacional intervention on
familial caregivers of ADpatients using the Caregiver Burden Scale applied before and
after the intervention. A positive impact of the psychoeducacional intervention was
observed.
Authors: Reisa A Sperling; Paul S Aisen; Laurel A Beckett; David A Bennett; Suzanne Craft; Anne M Fagan; Takeshi Iwatsubo; Clifford R Jack; Jeffrey Kaye; Thomas J Montine; Denise C Park; Eric M Reiman; Christopher C Rowe; Eric Siemers; Yaakov Stern; Kristine Yaffe; Maria C Carrillo; Bill Thies; Marcelle Morrison-Bogorad; Molly V Wagster; Creighton H Phelps Journal: Alzheimers Dement Date: 2011-04-21 Impact factor: 21.566
Authors: Eliasz Engelhardt; Sonia M T Brucki; José Luiz S Cavalcanti; Orestes V Forlenza; Jerson Laks; Francisco A C Vale Journal: Arq Neuropsiquiatr Date: 2005-12-15 Impact factor: 1.420