Association of shiftwork and leukocytes among national health and nutrition examination survey respondents.

Shift workers may experience disrupted sleep-wake or circadian cycles which, in turn, may lead to major health problems such as hypertension, obesity, and diabetes. Research indicates that shift workers have increased levels of leukocytes. Data from the National Health and Nutrition Examination Survey (2005-2010) examined the relationship between self-reported current shiftwork and leukocytes with adjustment for important confounders. Using linear regression, we found no association between shiftwork and leukocyte counts. Those not working had elevated levels compared to day workers but values in both groups were still within normal ranges. Additional research is needed to fully understand how shiftwork influences changes in leukocyte counts.