Literature DB >> 29211219

Incidence and Treatment of Chylothorax in Children Undergoing Corrective Surgery for Congenital Heart Diseases.

Nicolle Martin Christofe1, Cristiane Felix Ximenes Pessotti2, Laércio Paiva1, Ieda Biscegli Jatene2.   

Abstract

INTRODUCTION: Chylothorax is a lymphatic extravasation into pleural cavity and its incidence is 0.25%-5.3% in children undergoing cardiac surgery.
OBJECTIVE: To evaluate the incidence of chylothorax in pediatrics patients operated, linking it in each surgical intervention. Evaluate treatment types and efficiency.
METHODS: Retrospective study using medical records of children undergoing cardiac surgery in the Hospital do Coração between 2004 and 2014. For statistical analysis, qualitative variables by absolute frequency and relative frequency; quantitative variables, by median of 25 and 75 percentiles, as they did not present normal distribution (Shapiro-Wilk, P<0.05). The Chi-square test was used for the association between type of treatment and result. The adopted confidence level was 95%.
RESULTS: Incidence of chylothorax was 2.1% (0.9% in intracardiac surgery, 1.7% correction of patent ductus arteriosus and aortic coarctation, 8.3% Glenn's surgery, 11.8% total cavopulmonary surgery and 3% in others). Among treatments, fasting associated with total parenteral nutrition (TPN) resolved 51% of the cases. Hypoglossal diet had failed treatment and surgical referral in 22% of the cases. Fasting with TPN associated with octreotide had success in the treatment of chylothorax in a period exceeding 15 days in 78% of cases, and 3.7% were referred for surgery.
CONCLUSION: According to the results, incidence of chylothorax was 2.18%. Treatment with fasting and TPN leads to resolutions in 86.5%, and the association with octreotide was successful in 85.1% of cases, showing an efficient option, while the treatment with hypoglossal diet had therapeutic failure in 22% of the cases in which it was used.

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Year:  2017        PMID: 29211219      PMCID: PMC5701103          DOI: 10.21470/1678-9741-2017-0011

Source DB:  PubMed          Journal:  Braz J Cardiovasc Surg        ISSN: 0102-7638


  11 in total

1.  Use of octreotide in the treatment of chylothorax and chyloperitoneum.

Authors:  Cristiane Felix Ximenes Pessotti; Ieda Biscegli Jatene; Paulo Emanuel Uhrovcik Buononato; Patrícia Figueiredo Elias; Anna Carolina Domingues Pinto; Maria Fernanda Jensen Kok
Journal:  Arq Bras Cardiol       Date:  2011-08       Impact factor: 2.000

2.  [Chylothorax].

Authors:  Marcelo Alexandre Costa Vaz; Paulo Pêgo Fernandes
Journal:  J Bras Pneumol       Date:  2006       Impact factor: 2.624

3.  The management of chylothorax/chylopericardium following pediatric cardiac surgery: a 10-year experience.

Authors:  D M Nguyen; D Shum-Tim; A R Dobell; C I Tchervenkov
Journal:  J Card Surg       Date:  1995-07       Impact factor: 1.620

4.  Treatment of a persistent postoperative chylothorax with somatostatin.

Authors:  P C Rimensberger; B Müller-Schenker; A Kalangos; M Beghetti
Journal:  Ann Thorac Surg       Date:  1998-07       Impact factor: 4.330

5.  Etiology and management of pediatric chylothorax.

Authors:  M Beghetti; G La Scala; D Belli; P Bugmann; A Kalangos; C Le Coultre
Journal:  J Pediatr       Date:  2000-05       Impact factor: 4.406

6.  Chylothorax in children after congenital heart surgery.

Authors:  Shu-yan Chan; Wendy Lau; Wilfred H S Wong; Lik-cheung Cheng; Adolphus K T Chau; Yiu-fai Cheung
Journal:  Ann Thorac Surg       Date:  2006-11       Impact factor: 4.330

7.  Postoperative chylothorax after cardiothoracic surgery in children.

Authors:  Emily H Chan; Jennifer L Russell; William G Williams; Glen S Van Arsdell; John G Coles; Brian W McCrindle
Journal:  Ann Thorac Surg       Date:  2005-11       Impact factor: 4.330

Review 8.  Post-operative chylothorax in children: an evidence-based management algorithm.

Authors:  Charnchai Panthongviriyakul; Julie E Bines
Journal:  J Paediatr Child Health       Date:  2008-11-20       Impact factor: 1.954

Review 9.  Use of Monogen for pediatric postoperative chylothorax.

Authors:  Barbara E Cormack; Nigel J Wilson; Kirsten Finucane; Teena M West
Journal:  Ann Thorac Surg       Date:  2004-01       Impact factor: 4.330

10.  Incidence and treatment of chylothorax after cardiac surgery in children: analysis of a large multi-institution database.

Authors:  Carlos M Mery; Brady S Moffett; Muhammad S Khan; Wei Zhang; Francisco A Guzmán-Pruneda; Charles D Fraser; Antonio G Cabrera
Journal:  J Thorac Cardiovasc Surg       Date:  2013-11-15       Impact factor: 5.209

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  5 in total

1.  Medical Interventions for Chylothorax and their Impacts on Need for Surgical Intervention and Admission Characteristics: A Multicenter, Retrospective Insight.

Authors:  Rohit S Loomba; Joshua Wong; Megan Davis; Sarah Kane; Brian Heenan; Juan S Farias; Enrique G Villarreal; Saul Flores
Journal:  Pediatr Cardiol       Date:  2021-01-04       Impact factor: 1.655

Review 2.  Postoperative Chylothorax in Neonates and Infants after Congenital Heart Disease Surgery-Current Aspects in Diagnosis and Treatment.

Authors:  Georgios Samanidis; Georgios Kourelis; Stavroula Bounta; Meletios Kanakis
Journal:  Nutrients       Date:  2022-04-26       Impact factor: 6.706

Review 3.  Octreotide for Acquired Chylothorax in Pediatric Patients Post-Cardiothoracic Surgery for Congenital Heart Disease: A Systematic Review.

Authors:  A C Jenkinson; J McGuinness; T Prendiville
Journal:  Pediatr Cardiol       Date:  2022-10-18       Impact factor: 1.838

4.  How efficacious are Octreotide and Somatostatin in the management of chylothorax in congenital cardiac surgical patients?

Authors:  Sudharsan Madhavan; Masakazu Nakao
Journal:  Interact Cardiovasc Thorac Surg       Date:  2021-10-29

5.  Chemical pleurodesis and somatostatin in treating spontaneous chylothorax in pediatric patients: a retrospective analysis and review of the literature.

Authors:  Wei-Guang Long; Bin Cai; Jian-Ming Deng; Yang Liu; Wen-Jie Wang; Juan Luo
Journal:  Transl Pediatr       Date:  2020-08
  5 in total

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