Literature DB >> 29209917

Cluster analysis for syndromes of real-world coronary heart disease with angina pectoris.

Yufeng Zhao1,2, Xueyun Yu3, Xinyu Cao3,4, Lin Luo3, Liyun He3, Shusong Mao5, Li Ma5, Peijing Rong6, Yuxue Zhao6, Guozheng Li4,7, Baoyan Liu8,9.   

Abstract

Syndromes of coronary heart disease with angina pectoris were analyzed to provide guidance for clinical practice and to improve accuracy of traditional Chinese medicine (TCM) diagnoses and efficacy of TCM treatment. A total of 860 cases with coronary heart disease with angina pectoris were selected from TCM Clinical Research Information Sharing System for TCM clinics and research. Syndromes were automatically extracted with the cluster method and were analyzed to provide objective evidence for clinical studies. Final syndrome classifications were recognized and confirmed by clinical experts. Popular syndromes included Qi and blood deficiency, blood stasis and obstruction collaterals, liver depression and spleen deficiency, and Qi stagnation and blood stasis. Syndromes Qi and blood deficiency and blood stasis and obstruction collaterals accounted for 28.61% of total syndromes, whereas liver depression and spleen deficiency and Qi stagnation and blood stasis accounted for 26.44%. The main syndrome elements comprised Qi deficiency, blood deficiency, blood stasis, and Qi stagnation.

Entities:  

Keywords:  cluster analysis; coronary heart disease with angina pectoris; real-world study; syndrome differentiation

Mesh:

Year:  2017        PMID: 29209917     DOI: 10.1007/s11684-017-0556-1

Source DB:  PubMed          Journal:  Front Med        ISSN: 2095-0217            Impact factor:   4.592


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