Literature DB >> 29208694

Variation in Care and Clinical Outcomes in Children Hospitalized With Orbital Cellulitis.

Jessica L Markham1, Matthew Hall2,3, Jessica L Bettenhausen2, Angela L Myers2,4, Henry T Puls2, Russell J McCulloh2,4.   

Abstract

OBJECTIVES: To describe variation in the care of children hospitalized with orbital cellulitis and to determine associations with length of stay (LOS), emergency department (ED) revisits, and hospital readmissions.
METHODS: By using the Pediatric Health Information System, we performed a multicenter, retrospective study of children aged 2 months to 18 years with a primary International Classification of Diseases, Ninth Revision, Clinical Modification discharge diagnosis code for orbital cellulitis from 2007 to 2014. We assessed hospital-level variation in the use of diagnostic tests, corticosteroids, and antibiotics individually and in aggregate for association with outcomes (LOS, ED revisits, readmissions) after risk-adjusting for important clinical and demographic factors.
RESULTS: A total of 1828 children met inclusion criteria. Complete blood cell counts (median [interquartile range]: 81.8% [66.7-89.6]), C-reactive protein levels (57.1% [22.2-84.0]), blood cultures (57.9% [48.9-63.6]), and computed tomography imaging (74.7% [66.7-81.0]) were the most frequently performed diagnostic tests, with significant variation observed across hospitals (all P < .001). Corticosteroids were used in 29.2% of children (interquartile range: 18.4-37.5). There was significant variation in antibiotic exposure across hospitals (P < .001). Increased total diagnostic test usage was associated with increased LOS (P = .044), but not with 30-day ED revisits (P = .176) or readmissions (P = .403).
CONCLUSIONS: Children hospitalized with orbital cellulitis experience wide variation in clinical management. Increased hospital-level usage is associated with increased LOS. Our findings highlight a critical need to identify treatment strategies that optimize resource use and outcomes for children hospitalized with orbital cellulitis.
Copyright © 2018 by the American Academy of Pediatrics.

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Year:  2017        PMID: 29208694     DOI: 10.1542/hpeds.2017-0040

Source DB:  PubMed          Journal:  Hosp Pediatr        ISSN: 2154-1671


  7 in total

Review 1.  Applying Pharmacodynamics and Antimicrobial Stewardship to Pediatric Preseptal and Orbital Cellulitis.

Authors:  Grant T Stimes; Jennifer E Girotto
Journal:  Paediatr Drugs       Date:  2019-12       Impact factor: 3.022

Review 2.  Epidemiology and Management of Orbital Cellulitis in Children.

Authors:  Brenda I Anosike; Veena Ganapathy; Mari M Nakamura
Journal:  J Pediatric Infect Dis Soc       Date:  2022-05-30       Impact factor: 5.235

3.  Corticosteroids for periorbital and orbital cellulitis.

Authors:  Emily Kornelsen; Sanjay Mahant; Patricia Parkin; Lily Yuxi Ren; Yohann A Reginald; Samir S Shah; Peter J Gill
Journal:  Cochrane Database Syst Rev       Date:  2021-04-28

4.  Opportunities for Stewardship in the Transition From Intravenous to Enteral Antibiotics in Hospitalized Pediatric Patients.

Authors:  Jillian M Cotter; Matt Hall; Sonya Tang Girdwood; John R Stephens; Jessica L Markham; James C Gay; Samir S Shah
Journal:  J Hosp Med       Date:  2021-02       Impact factor: 2.960

5.  Care and outcomes of Canadian children hospitalised with periorbital and orbital cellulitis: protocol for a multicentre, retrospective cohort study.

Authors:  Peter J Gill; Patricia C Parkin; Nurshad Begum; Olivier Drouin; Jessica Foulds; Catherine Pound; Julie Quet; Gemma Vomiero; Gita Wahi; Mahmoud Sakran; Natascha Kozlowski; Ann Bayliss; Ronik Kanani; Anupam Sehgal; Eleanor M Pullenayegum; Arun Reginald; Nikolaus Wolter; Sanjay Mahant
Journal:  BMJ Open       Date:  2019-12-22       Impact factor: 2.692

6.  Prediction across healthcare settings: a case study in predicting emergency department disposition.

Authors:  Andrew M Fine; Ben Y Reis; Yuval Barak-Corren; Pradip Chaudhari; Jessica Perniciaro; Mark Waltzman
Journal:  NPJ Digit Med       Date:  2021-12-15

7.  Readmissions Following Hospitalization for Infection in Children With or Without Medical Complexity.

Authors:  Jessica L Markham; Matt Hall; Jennifer L Goldman; Jessica L Bettenhausen; James C Gay; James Feinstein; Julia Simmons; Stephanie K Doupnik; Jay G Berry
Journal:  J Hosp Med       Date:  2021-03       Impact factor: 2.960

  7 in total

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