Literature DB >> 2920800

Chronic cadmium intake results in dose-related excretion of metallothionein in urine.

Z A Shaikh1, K M Harnett, S A Perlin, P C Huang.   

Abstract

Urinary excretion of metallothionein was measured by radioimmunoassay in rats given drinking water containing 5 or 50 mg cadmium/l for up to 2 years. The metallothionein levels corresponded to the concentration of cadmium in the drinking water and increased linearly over the course of the study. These results demonstrate that urinary metallothionein is a sensitive biological indicator of oral cadmium exposure.

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Year:  1989        PMID： 2920800     DOI： 10.1007/BF01954852

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Metallothionein in plasma and urine of cadmium workers.

Authors:  G F Nordberg; J S Garvey; C C Chang
Journal:  Environ Res       Date:  1982-06       Impact factor: 6.498

2.  Critical concentration of cadmium for renal toxicity in rats.

Authors:  C Tohyama; N Sugihira; H Saito
Journal:  J Toxicol Environ Health       Date:  1987

3.  Urinary metallothionein and tissue metal levels of rats injected with cadmium, mercury, lead, copper or zinc.

Authors:  Y H Lee; Z A Shaikh; C Tohyama
Journal:  Toxicology       Date:  1983 Jul-Aug       Impact factor: 4.221

4.  Metallothionein excretion in urine upon cadmium exposure: its relationship with liver and kidney cadmium.

Authors:  C Tohyama; Z A Shaikh; K J Ellis; S H Cohn
Journal:  Toxicology       Date:  1981       Impact factor: 4.221

5.  Dose-related alterations in growth and mineral disposition by chronic oral cadmium administration in the male rat.

Authors:  E M Yuhas; T S Miya; R C Schnell
Journal:  Toxicology       Date:  1979-01       Impact factor: 4.221

6.  Metallothionein and occupational exposure to cadmium.

Authors:  F Y Falck; L J Fine; R G Smith; J Garvey; A Schork; B England; K D McClatchey; J Linton
Journal:  Br J Ind Med       Date:  1983-08

7.  Aversiveness of cadmium in solution.

Authors:  D A Cory-Slechta; B Weiss
Journal:  Neurotoxicology       Date:  1981-12       Impact factor: 4.294

8.  Elevated urinary excretion of metallothionein due to environmental cadmium exposure.

Authors:  C Tohyama; Z A Shaikh; K Nogawa; E Kobayashi; R Honda
Journal:  Toxicology       Date:  1981       Impact factor: 4.221

9.  Occupational exposure to cadmium: effect on metallothionein and other biological indices of exposure and renal function.

Authors:  Z A Shaikh; C Tohyama; C V Nolan
Journal:  Arch Toxicol       Date:  1987-02       Impact factor: 5.153

10.  Urinary metallothionein as an indicator of cadmium body burden and of cadmium-induced nephrotoxicity.

Authors:  Z A Shaikh; C Tohyama
Journal:  Environ Health Perspect       Date:  1984-03       Impact factor: 9.031
  10 in total

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