Literature DB >> 29207731

Sodium Valproate Induced Alopecia: A Case Series.

Sereen Rose Thomson1, Vinay Mamulpet1, Shalini Adiga2.   

Abstract

Drug induced alopecia may range from a barely detectable shedding to an irreversible baldness. Alopecia associated with valproate is a dose-dependent and reversible side effect. We hereby report, three cases of alopecia that occurred in patients who received sodium valproate for various neurological conditions. In all three cases, long term exposure of valproate therapy led to the development of alopecia which eventually resolved after dose reduction or discontinuation. The Naranjo's causality assessment scale indicated valproate as the probable cause of the alopecia in all our patients.

Entities:  

Keywords:  Adverse drug reaction; Anticonvulsant; Hair loss; Naranjo’s scale

Year:  2017        PMID: 29207731      PMCID: PMC5713753          DOI: 10.7860/JCDR/2017/28564.10658

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  8 in total

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5.  Correlation between plasma ammonia level and serum trough concentration of free valproic acid in patients with epilepsy.

Authors:  Hiroki Itoh; Yosuke Suzuki; Kanako Fujisaki; Yuhki Sato; Masaharu Takeyama
Journal:  Biol Pharm Bull       Date:  2012       Impact factor: 2.233

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Journal:  Epilepsy Behav       Date:  2014-12-13       Impact factor: 2.937

7.  Dose-dependent valproate-induced alopecia in patients with mental disorders.

Authors:  Takashi Tomita; Hidekazu Goto; Tadashi Yoshida; Katsuya Tanaka; Kenji Sumiya; Yukinao Kohda
Journal:  Indian J Pharmacol       Date:  2015 Nov-Dec       Impact factor: 1.200

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Authors:  Suresh K Ramakrishnappa; Mahesh N Belhekar
Journal:  Indian J Pharmacol       Date:  2013 Mar-Apr       Impact factor: 1.200

  8 in total
  1 in total

1.  Direct-acting oral anticoagulants and alopecia: The valuable support of postmarketing data.

Authors:  Giulia Bonaldo; Alberto Vaccheri; Domenico Motola
Journal:  Br J Clin Pharmacol       Date:  2020-02-18       Impact factor: 4.335

  1 in total

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