Literature DB >> 29207719

Approach to a Pregnant Woman with Anti D + Anti C Reactivity Pattern: A Diagnostic Conundrum.

Preeti Rai1, Geetika Sharma2, Deeksha Singh3, Jyoti Garg4.   

Abstract

The Rhesus G antigen is present on all RBCs that are C+ and also on most D+ RBCs. Due to this co-distribution of G with either C or D antigen, it mimics a reactivity pattern of anti C + anti D on Indirect Antiglobulin Test (IAT), though the role of Anti G in causing Hemolytic Disease of Newborn (HDN) is controversial. The differentiation of anti D, anti C, and anti G is essential particularly in pregnant females. We hereby report a rare case of anti G with anti D and anti C in a pregnant woman with emphasis on approach to identify anti D+C+G and its implications.

Entities:  

Keywords:  Alloimmunisation; Anti C; Anti D; Anti G; Haemolytic; Irregular erythrocyte antibodies; Pregnancy

Year:  2017        PMID： 29207719      PMCID： PMC5713741          DOI： 10.7860/JCDR/2017/27902.10550

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN： 0973-709X


  17 in total

1.  A new Rh blood type which reveals the Rh antigen G.

Authors:  F H ALLEN; P A TIPPETT
Journal:  Vox Sang       Date:  1958-09       Impact factor: 2.144

2.  Twin pregnancy complicated by severe hemolytic disease of the fetus and newborn due to anti-g and anti-C.

Authors:  Thomas N Trevett; Kenneth J Moise
Journal:  Obstet Gynecol       Date:  2005-11       Impact factor: 7.661

3.  Case report: moderate hemolytic disease of the newborn due to anti-G.

Authors:  A R Huber; G T Leonard; R W Driggers; S B Learn; C W Gilstad
Journal:  Immunohematology       Date:  2006

4.  Anti Rh Hemolytic Disease due to Anti C Antibody: Is Testing for Anti D Antibodies Enough?

Authors:  Gita Negi; Gaur Dushyant Singh
Journal:  Indian J Hematol Blood Transfus       Date:  2011-08-28       Impact factor: 0.900

5.  Involvement of Ser103 of the Rh polypeptides in G epitope formation.

Authors:  B H Faas; E A Beckers; S Simsek; M A Overbeeke; R Pepper; D J van Rhenen; A E von dem Borne; C E van der Schoot
Journal:  Transfusion       Date:  1996-06       Impact factor: 3.157

6.  A simple approach to confirm the presence of anti-D in sera with presumed anti-D+C specificity.

Authors:  Fátima Baía; Eduardo Muñiz-Diaz; Neus Boto; Marta Salgado; Rosa Montero; Teresa Ventura; Helena Sousa; Branca Alves; Núria Nogués; Carmen Koch
Journal:  Blood Transfus       Date:  2013-01-23       Impact factor: 3.443

7.  Red blood cell antibodies in pregnancy and their clinical consequences: synergistic effects of multiple specificities.

Authors:  Maria Nordvall; Morten Dziegiel; Hanne Kristine Hegaard; Mogens Bidstrup; Finn Jonsbo; Birgit Christensen; Morten Hedegaard
Journal:  Transfusion       Date:  2009-05-27       Impact factor: 3.157

8.  Development of Anti-G, Anti-C and Anti-Jk(b) in a 22-Year-Old Mother during Her Fourth Pregnancy.

Authors:  Torsten J Schulze; Meike Goebel; Erwin A Scharberg; Peter Bugert; Karin Janetzko
Journal:  Transfus Med Hemother       Date:  2013-05-17       Impact factor: 3.747

9.  Anti-G antibody in alloimmunized pregnant women: Report of two cases.

Authors:  Raj Nath Makroo; Anita Kaul; Aakanksha Bhatia; Soma Agrawal; Chanchal Singh; Prashant Karna
Journal:  Asian J Transfus Sci       Date:  2015 Jul-Dec

10.  Anti-G with concomitant anti-C and anti-D: A case report in a pregnant woman.

Authors:  Rabeya Yousuf; Ahmad Nasirudin Mustafa; Siew-Ling Ho; Yee-Loong Tang; Chooi-Fun Leong
Journal:  Asian J Transfus Sci       Date:  2017 Jan-Jun
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