| Literature DB >> 29207257 |
Alexis Lomakin1, Guilherme Nader2, Matthieu Piel3.
Abstract
Nuclear pore complexes tightly regulate nucleo-cytoplasmic transport, controlling the nuclear concentration of several transcription factors. In a recent issue of Cell, Elosegui-Artola et al. (2017) show that nuclear deformation modulates the nuclear entry rates of YAP/TAZ via nuclear pore stretching, clarifying how forces affect gene transcription.Entities:
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Year: 2017 PMID： 29207257 DOI： 10.1016/j.devcel.2017.11.015
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270