Literature DB >> 29206448

Ni-Al Bimetallic Catalyzed Enantioselective Cycloaddition of Cyclopropyl Carboxamide with Alkyne.

Qi-Sheng Liu1, De-Yin Wang1, Zhi-Jun Yang1, Yu-Xin Luan1, Jin-Fei Yang1, Jiang-Fei Li1, You-Ge Pu1, Mengchun Ye1,2.   

Abstract

A Ni-Al bimetallic catalyzed enantioselective cycloaddition reaction of cyclopropyl carboxamides with alkynes has been developed. A series of cyclopentenyl carboxamides were obtained in up to 99% yield and 94% ee. The bifunctional-ligand-enabled bimetallic catalysis proved to be an efficient strategy for the C-C bond cleavage of unreactive cyclopropanes.

Entities:  

Year:  2017        PMID： 29206448     DOI： 10.1021/jacs.7b09947

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  4 in total

1.  Ni-catalyzed hydroarylation of alkynes with unactivated β-C(sp2)-H bonds.

Authors:  Shao-Long Qi; Yu-Peng Liu; Yi Li; Yu-Xin Luan; Mengchun Ye
Journal:  Nat Commun       Date:  2022-05-26       Impact factor: 17.694

2.  Enantioselective Ruthenium-Catalyzed Benzocyclobutenone-Ketol Cycloaddition: Merging C-C Bond Activation and Transfer Hydrogenative Coupling for Type II Polyketide Construction.

Authors:  Brett R Ambler; Ben W H Turnbull; Sankar Rao Suravarapu; Maulen M Uteuliyev; Nancy O Huynh; Michael J Krische
Journal:  J Am Chem Soc       Date:  2018-07-11       Impact factor: 15.419

3.  An endo-Directing-Group Strategy Unlocks Enantioselective (3+1+2) Carbonylative Cycloadditions of Aminocyclopropanes.

Authors:  Olga O Sokolova; John F Bower
Journal:  Angew Chem Int Ed Engl       Date:  2022-06-24       Impact factor: 16.823

4.  Construction 7-membered ring via Ni-Al bimetal-enabled C-H cyclization for synthesis of tricyclic imidazoles.

Authors:  Jiang-Fei Li; Wei-Wei Xu; Rong-Hua Wang; Yue Li; Ge Yin; Mengchun Ye
Journal:  Nat Commun       Date:  2021-05-24       Impact factor: 14.919
  4 in total

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