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Literature DB >> 29203338

The PAQosome, an R2TP-Based Chaperone for Quaternary Structure Formation.

Walid A Houry¹, Edouard Bertrand², Benoit Coulombe³.

Abstract

The Rvb1-Rvb2-Tah1-Pih1/prefoldin-like (R2TP/PFDL) complex is a unique chaperone that provides a platform for the assembly and maturation of many key multiprotein complexes in mammalian cells. Here, we propose to rename R2TP/PFDL as PAQosome (particle for arrangement of quaternary structure) to more accurately represent its unique function.

Entities: Gene Species

Keywords: R2TP; complex assembly; molecular chaperone; prefoldin; quaternary structure

Mesh：

Substances：

Year: 2017 PMID： 29203338 DOI： 10.1016/j.tibs.2017.11.001

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

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