| Literature DB >> 29201659 |
J Scuffell1, D Boccia2, F Garcia Velarde3, S R Leon3, G Raviola4, L Lecca3,4, J T Galea3,4.
Abstract
Mental disorders and alcohol/drug use worsen treatment outcomes for multidrug-resistant tuberculosis (TB), but data are lacking for extensively drug-resistant (XDR) TB. We investigated the association of baseline mental disorders and alcohol/drug use on XDR-TB treatment outcomes in a retrospective study of 53 XDR-TB Peruvian patients during 2010-2012. Logistic regression estimated the odds ratios for unfavourable XDR-TB treatment outcomes. Overall treatment success was 25%. Mental disorders and drug/alcohol use were found in respectively 22.4% and 20.4% of patients; neither were associated with unfavourable treatment outcomes. Future research should explore the relationship between mental health and drug/alcohol use in XDR-TB treatment outcomes.Entities:
Keywords: XDR-TB; alcohol; anxiety; depression; psychosis
Year: 2017 PMID: 29201659 PMCID: PMC5677000 DOI: 10.5588/pha.17.0044
Source DB: PubMed Journal: Public Health Action ISSN: 2220-8372