Literature DB >> 2920039

Molecular cloning of the human transmembrane secretory component (poly-Ig receptor) and its mRNA expression in human tissues.

P Krajci1, R Solberg, M Sandberg, O Oyen, T Jahnsen, P Brandtzaeg.   

Abstract

A 2.5 kilobase (kb) cDNA clone containing 92% of the coding region for human transmembrane secretory component (SC) or poly-Ig receptor, was isolated from a mammary gland cDNA library. The cDNA clone encoded a protein of 693 amino acids which showed 99% homology with the primary amino acid sequence of human free SC as reported by Eiffert et al. (1), and 54% homology with the deduced amino acid sequence of rabbit transmembrane SC for which cDNA was cloned by Mostov et al. (2). Northern blot analysis showed mRNA expression in various human exocrine tissues in good agreement with our previous immunohistochemical studies of SC.

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Year:  1989        PMID： 2920039     DOI： 10.1016/0006-291x(89)92790-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  17 in total

1.  Multiple features contribute to efficient constitutive splicing of an unusually large exon.

Authors:  S R Bruce; M L Peterson
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2.  Multiple cleavage sites for polymeric immunoglobulin receptor.

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Review 3.  The role of secretory antibodies in infection immunity.

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4.  The human transmembrane secretory component (poly-Ig receptor): molecular cloning, restriction fragment length polymorphism and chromosomal sublocalization.

Authors:  P Krajci; K H Grzeschik; A H Geurts van Kessel; B Olaisen; P Brandtzaeg
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Review 5.  Molecular and cellular mechanisms involved in transepithelial transport.

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Authors:  C Vincent; G Cozon; M Zittoun; M Mellquist; M D Kazatchkine; C Czerkinsky; J P Revillard
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8.  Tumour necrosis factor-alpha-mediated human polymeric immunoglobulin receptor expression is regulated by both mitogen-activated protein kinase and phosphatidylinositol-3-kinase in HT-29 cell line.

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9.  Ontogeny of the secretory immune system: maturation of a functional polymeric immunoglobulin receptor regulated by gene expression.

Authors:  S Huling; G R Fournier; A Feren; A Chuntharapai; A L Jones
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-15       Impact factor: 11.205

10.  Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.

Authors:  Wataru Obara; Aritoshi Iida; Yasushi Suzuki; Toshihiro Tanaka; Fumihiro Akiyama; Shiro Maeda; Yozo Ohnishi; Ryo Yamada; Tatsuhiko Tsunoda; Takashi Takei; Kyoko Ito; Kazuho Honda; Keiko Uchida; Ken Tsuchiya; Wako Yumura; Takashi Ujiie; Yutaka Nagane; Kosaku Nitta; Satoru Miyano; Ichiei Narita; Fumitake Gejyo; Hiroshi Nihei; Tomoaki Fujioka; Yusuke Nakamura
Journal:  J Hum Genet       Date:  2003-05-10       Impact factor: 3.172
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